Chemical structure and antifungal activity of mint essential oil components
2020
Preuzimanje 🢃
Autori
Plavšić, DraganaSkrinjar, Marija M.
Psodorov, Dorde B.
Pezo, Lato
Milovanović, Ivan L. J.
Psodorov, Dragan D.
Kojić, Predrag
Kocić-Tanackov, Suncica
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The objective of this research was to determine chemical composition and to evaluate the antifungal activity of essential oil of Mentha piperita. By the application of GC/MS analysis of essential mint oil, 27 components were identified. The major components were menthol (39.9 %), menton (23.51 %), menthyl acetate (7.29 %), 1.8-cineol (5.96 %), isomenton (5.24 %), isomenthol (3.17 %), trans-caryophyllene (2.88 %), limonene (2.14 %), pulegon (1.38 %), beta-pinene (1.14 %) and piperiton (1.03 %). The quantitative structure-retention relationship (QSRR) was employed to predict the retention time (RT) of Mentha piperita essential oil compounds obtained in GC/MS analysis, using twelve molecular descriptors selected by genetic algorithm. The selected descriptors were used, as inputs of an artificial neural network, to build an RT predictive QSRR model. The coefficient of determination was 0.983, during training cycle, indicating that this model could be used for prediction of RT values for es...sential oil compounds in Mentha piperita essential oil extracts. Essential oil of Mentha piperita showed antifungal activity on all tested isolates in the minimal inhibitory concentration range of 0.2-1.7 mu l/ml and a minimal fungicidal concentration (MFC) range of 1.7-454.5 mu l/ml. The most powerful antifungal activity of mint was observed in C. cladosporioides of MFC value 1.7 mu l/ml. P. aurantiogriseum showed the lowest sensitivity of MFC value 454.5 mu l/ml.
Ključne reči:
QSRR / genetic algorithm / antimicrobial potential / ANNIzvor:
Journal of the Serbian Chemical Society, 2020, 85, 9, 1149-1161Izdavač:
- Srpsko hemijsko društvo, Beograd
Finansiranje / projekti:
- Funkcionalni proizvodi na bazi žita namenjeni osobama sa metaboličkim poremećajima (RS-MESTD-Technological Development (TD or TR)-31029)
DOI: 10.2298/JSC191210017P
ISSN: 0352-5139
WoS: 000573967900004
Scopus: 2-s2.0-85094886173
Institucija/grupa
Institut za opštu i fizičku hemijuTY - JOUR AU - Plavšić, Dragana AU - Skrinjar, Marija M. AU - Psodorov, Dorde B. AU - Pezo, Lato AU - Milovanović, Ivan L. J. AU - Psodorov, Dragan D. AU - Kojić, Predrag AU - Kocić-Tanackov, Suncica PY - 2020 UR - https://riofh.iofh.bg.ac.rs/handle/123456789/758 AB - The objective of this research was to determine chemical composition and to evaluate the antifungal activity of essential oil of Mentha piperita. By the application of GC/MS analysis of essential mint oil, 27 components were identified. The major components were menthol (39.9 %), menton (23.51 %), menthyl acetate (7.29 %), 1.8-cineol (5.96 %), isomenton (5.24 %), isomenthol (3.17 %), trans-caryophyllene (2.88 %), limonene (2.14 %), pulegon (1.38 %), beta-pinene (1.14 %) and piperiton (1.03 %). The quantitative structure-retention relationship (QSRR) was employed to predict the retention time (RT) of Mentha piperita essential oil compounds obtained in GC/MS analysis, using twelve molecular descriptors selected by genetic algorithm. The selected descriptors were used, as inputs of an artificial neural network, to build an RT predictive QSRR model. The coefficient of determination was 0.983, during training cycle, indicating that this model could be used for prediction of RT values for essential oil compounds in Mentha piperita essential oil extracts. Essential oil of Mentha piperita showed antifungal activity on all tested isolates in the minimal inhibitory concentration range of 0.2-1.7 mu l/ml and a minimal fungicidal concentration (MFC) range of 1.7-454.5 mu l/ml. The most powerful antifungal activity of mint was observed in C. cladosporioides of MFC value 1.7 mu l/ml. P. aurantiogriseum showed the lowest sensitivity of MFC value 454.5 mu l/ml. PB - Srpsko hemijsko društvo, Beograd T2 - Journal of the Serbian Chemical Society T1 - Chemical structure and antifungal activity of mint essential oil components EP - 1161 IS - 9 SP - 1149 VL - 85 DO - 10.2298/JSC191210017P UR - conv_880 ER -
@article{ author = "Plavšić, Dragana and Skrinjar, Marija M. and Psodorov, Dorde B. and Pezo, Lato and Milovanović, Ivan L. J. and Psodorov, Dragan D. and Kojić, Predrag and Kocić-Tanackov, Suncica", year = "2020", abstract = "The objective of this research was to determine chemical composition and to evaluate the antifungal activity of essential oil of Mentha piperita. By the application of GC/MS analysis of essential mint oil, 27 components were identified. The major components were menthol (39.9 %), menton (23.51 %), menthyl acetate (7.29 %), 1.8-cineol (5.96 %), isomenton (5.24 %), isomenthol (3.17 %), trans-caryophyllene (2.88 %), limonene (2.14 %), pulegon (1.38 %), beta-pinene (1.14 %) and piperiton (1.03 %). The quantitative structure-retention relationship (QSRR) was employed to predict the retention time (RT) of Mentha piperita essential oil compounds obtained in GC/MS analysis, using twelve molecular descriptors selected by genetic algorithm. The selected descriptors were used, as inputs of an artificial neural network, to build an RT predictive QSRR model. The coefficient of determination was 0.983, during training cycle, indicating that this model could be used for prediction of RT values for essential oil compounds in Mentha piperita essential oil extracts. Essential oil of Mentha piperita showed antifungal activity on all tested isolates in the minimal inhibitory concentration range of 0.2-1.7 mu l/ml and a minimal fungicidal concentration (MFC) range of 1.7-454.5 mu l/ml. The most powerful antifungal activity of mint was observed in C. cladosporioides of MFC value 1.7 mu l/ml. P. aurantiogriseum showed the lowest sensitivity of MFC value 454.5 mu l/ml.", publisher = "Srpsko hemijsko društvo, Beograd", journal = "Journal of the Serbian Chemical Society", title = "Chemical structure and antifungal activity of mint essential oil components", pages = "1161-1149", number = "9", volume = "85", doi = "10.2298/JSC191210017P", url = "conv_880" }
Plavšić, D., Skrinjar, M. M., Psodorov, D. B., Pezo, L., Milovanović, I. L. J., Psodorov, D. D., Kojić, P.,& Kocić-Tanackov, S.. (2020). Chemical structure and antifungal activity of mint essential oil components. in Journal of the Serbian Chemical Society Srpsko hemijsko društvo, Beograd., 85(9), 1149-1161. https://doi.org/10.2298/JSC191210017P conv_880
Plavšić D, Skrinjar MM, Psodorov DB, Pezo L, Milovanović ILJ, Psodorov DD, Kojić P, Kocić-Tanackov S. Chemical structure and antifungal activity of mint essential oil components. in Journal of the Serbian Chemical Society. 2020;85(9):1149-1161. doi:10.2298/JSC191210017P conv_880 .
Plavšić, Dragana, Skrinjar, Marija M., Psodorov, Dorde B., Pezo, Lato, Milovanović, Ivan L. J., Psodorov, Dragan D., Kojić, Predrag, Kocić-Tanackov, Suncica, "Chemical structure and antifungal activity of mint essential oil components" in Journal of the Serbian Chemical Society, 85, no. 9 (2020):1149-1161, https://doi.org/10.2298/JSC191210017P ., conv_880 .