Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches
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Аутори
Masković, Pavle![](/themes/Mirageriofh/images/orcid.png)
Veličković, Vesna
Đurović, Saša
![](/themes/Mirageriofh/images/orcid.png)
Zeković, Zoran
![](/themes/Mirageriofh/images/orcid.png)
Radojković, Marija
![](/themes/Mirageriofh/images/orcid.png)
Cvetanović, Aleksandra
![](/themes/Mirageriofh/images/orcid.png)
Svarc-Gajić, Jaroslava
![](/themes/Mirageriofh/images/orcid.png)
Mitić, Milan
![](/themes/Mirageriofh/images/orcid.png)
Vujić, Jelena
Чланак у часопису (Објављена верзија)
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Метаподаци
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Background: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. Purpose: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. Study design and methods: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cel...l lines for cytotoxic and fifteen bacterial strain for antibacterial activity. Results and conclusion: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.
Кључне речи:
Lavatera thuringiaca L. / HPLC-DAD analysis / Extraction / Chemical composition / Biological activityИзвор:
Phytomedicine, 2018, 38, 118-124
DOI: 10.1016/j.phymed.2017.11.010
ISSN: 0944-7113
PubMed: 29425643
WoS: 000425172900013
Scopus: 2-s2.0-85036501417
Институција/група
Institut za opštu i fizičku hemijuTY - JOUR AU - Masković, Pavle AU - Veličković, Vesna AU - Đurović, Saša AU - Zeković, Zoran AU - Radojković, Marija AU - Cvetanović, Aleksandra AU - Svarc-Gajić, Jaroslava AU - Mitić, Milan AU - Vujić, Jelena PY - 2018 UR - https://riofh.iofh.bg.ac.rs/handle/123456789/604 AB - Background: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. Purpose: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. Study design and methods: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. Results and conclusion: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds. T2 - Phytomedicine T1 - Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches EP - 124 SP - 118 VL - 38 DO - 10.1016/j.phymed.2017.11.010 UR - conv_708 ER -
@article{ author = "Masković, Pavle and Veličković, Vesna and Đurović, Saša and Zeković, Zoran and Radojković, Marija and Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Mitić, Milan and Vujić, Jelena", year = "2018", abstract = "Background: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. Purpose: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. Study design and methods: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. Results and conclusion: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.", journal = "Phytomedicine", title = "Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches", pages = "124-118", volume = "38", doi = "10.1016/j.phymed.2017.11.010", url = "conv_708" }
Masković, P., Veličković, V., Đurović, S., Zeković, Z., Radojković, M., Cvetanović, A., Svarc-Gajić, J., Mitić, M.,& Vujić, J.. (2018). Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches. in Phytomedicine, 38, 118-124. https://doi.org/10.1016/j.phymed.2017.11.010 conv_708
Masković P, Veličković V, Đurović S, Zeković Z, Radojković M, Cvetanović A, Svarc-Gajić J, Mitić M, Vujić J. Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches. in Phytomedicine. 2018;38:118-124. doi:10.1016/j.phymed.2017.11.010 conv_708 .
Masković, Pavle, Veličković, Vesna, Đurović, Saša, Zeković, Zoran, Radojković, Marija, Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Mitić, Milan, Vujić, Jelena, "Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches" in Phytomedicine, 38 (2018):118-124, https://doi.org/10.1016/j.phymed.2017.11.010 ., conv_708 .