Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts
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Autori
Filip, SnežanaĐurović, Saša
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Blagojević, Stevan
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Tomić, Ana
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Ranitović, Aleksandra
Gašić, Uroš
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Tešić, Živoslav
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Zeković, Zoran
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Članak u časopisu (Objavljena verzija)
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Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra-high-performance liquid chromatography, with a diode array detector coupled with triple-quadrupole mass spectrometer and gas chromatography-mass spectrometry techniques. Thirty-one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5-O-caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram-positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATC...C 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties.
Ključne reči:
Moraceae / Maclura pomifera (Osage orange) / leaf extraction / chemical profile / antimicrobial activityIzvor:
Archiv der Pharmazie, 2021, 354, 2Izdavač:
- Weinheim: Wiley-VCH Verlag Gmbh
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200007 (Univerzitet u Beogradu, Institut za biološka istraživanja 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200051 (Institut za opštu i fizičku hemiju, Beograd) (RS-MESTD-inst-2020-200051)
DOI: 10.1002/ardp.202000195
ISSN: 0365-6233
PubMed: 33049077
WoS: 000585342500001
Scopus: 2-s2.0-85092402429
Institucija/grupa
Institut za opštu i fizičku hemijuTY - JOUR AU - Filip, Snežana AU - Đurović, Saša AU - Blagojević, Stevan AU - Tomić, Ana AU - Ranitović, Aleksandra AU - Gašić, Uroš AU - Tešić, Živoslav AU - Zeković, Zoran PY - 2021 UR - https://riofh.iofh.bg.ac.rs/handle/123456789/794 AB - The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra-high-performance liquid chromatography, with a diode array detector coupled with triple-quadrupole mass spectrometer and gas chromatography-mass spectrometry techniques. Thirty-one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5-O-caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram-positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATCC 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties. PB - Weinheim: Wiley-VCH Verlag Gmbh T2 - Archiv der Pharmazie T1 - Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts IS - 2 VL - 354 DO - 10.1002/ardp.202000195 UR - conv_886 ER -
@article{ author = "Filip, Snežana and Đurović, Saša and Blagojević, Stevan and Tomić, Ana and Ranitović, Aleksandra and Gašić, Uroš and Tešić, Živoslav and Zeković, Zoran", year = "2021", abstract = "The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra-high-performance liquid chromatography, with a diode array detector coupled with triple-quadrupole mass spectrometer and gas chromatography-mass spectrometry techniques. Thirty-one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5-O-caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram-positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATCC 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties.", publisher = "Weinheim: Wiley-VCH Verlag Gmbh", journal = "Archiv der Pharmazie", title = "Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts", number = "2", volume = "354", doi = "10.1002/ardp.202000195", url = "conv_886" }
Filip, S., Đurović, S., Blagojević, S., Tomić, A., Ranitović, A., Gašić, U., Tešić, Ž.,& Zeković, Z.. (2021). Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts. in Archiv der Pharmazie Weinheim: Wiley-VCH Verlag Gmbh., 354(2). https://doi.org/10.1002/ardp.202000195 conv_886
Filip S, Đurović S, Blagojević S, Tomić A, Ranitović A, Gašić U, Tešić Ž, Zeković Z. Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts. in Archiv der Pharmazie. 2021;354(2). doi:10.1002/ardp.202000195 conv_886 .
Filip, Snežana, Đurović, Saša, Blagojević, Stevan, Tomić, Ana, Ranitović, Aleksandra, Gašić, Uroš, Tešić, Živoslav, Zeković, Zoran, "Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts" in Archiv der Pharmazie, 354, no. 2 (2021), https://doi.org/10.1002/ardp.202000195 ., conv_886 .