TY  - JOUR
AU  - Đurović, Saša
AU  - Micić, Darko
AU  - Sorgić, Sasa
AU  - Popov, Sasa
AU  - Gašić, Uroš
AU  - Tosti, Tomislav
AU  - Kostić, Marija
AU  - Smyatskaya, Yulia A.
AU  - Blagojević, Stevan
AU  - Zeković, Zoran
PY  - 2023
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/1005
AB  - Stinging nettle (SN) is an extraordinary plant from the Urticaceae botanical family. It is well-known and widely used in food and folk medicine to treat different disorders and diseases. This article aimed to study the chemical composition of SN leaves extracts, i.e., polyphenolic compounds and vitamins B and C, because many studies ascribed high biological potency to these compounds and their significance in the human diet. Besides the chemical profile, the thermal properties of the extracts were studied. The results confirmed presence of many polyphenolic compounds and vitamins B and C. It also showed that the chemical profile closely correlated with the applied extraction technique. The thermal analysis showed that analyzed samples were thermally stable up to about 160 degrees C. Thermal degradation of samples UAE, MAE, and MAC took place in four steps, and sample SE in three steps. Altogether, results confirmed the presence of health-beneficial compounds in stinging nettle leaves and indicated the possible application of its extract in pharmaceutical and food industries as both a medicinal and food additive.
PB  - MDPI AG
T2  - Molecules
T1  - Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts
IS  - 5
VL  - 28
DO  - 10.3390/molecules28052278
UR  - conv_1087
ER  - 

@article{
author = "Đurović, Saša and Micić, Darko and Sorgić, Sasa and Popov, Sasa and Gašić, Uroš and Tosti, Tomislav and Kostić, Marija and Smyatskaya, Yulia A. and Blagojević, Stevan and Zeković, Zoran",
year = "2023",
abstract = "Stinging nettle (SN) is an extraordinary plant from the Urticaceae botanical family. It is well-known and widely used in food and folk medicine to treat different disorders and diseases. This article aimed to study the chemical composition of SN leaves extracts, i.e., polyphenolic compounds and vitamins B and C, because many studies ascribed high biological potency to these compounds and their significance in the human diet. Besides the chemical profile, the thermal properties of the extracts were studied. The results confirmed presence of many polyphenolic compounds and vitamins B and C. It also showed that the chemical profile closely correlated with the applied extraction technique. The thermal analysis showed that analyzed samples were thermally stable up to about 160 degrees C. Thermal degradation of samples UAE, MAE, and MAC took place in four steps, and sample SE in three steps. Altogether, results confirmed the presence of health-beneficial compounds in stinging nettle leaves and indicated the possible application of its extract in pharmaceutical and food industries as both a medicinal and food additive.",
publisher = "MDPI AG",
journal = "Molecules",
title = "Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts",
number = "5",
volume = "28",
doi = "10.3390/molecules28052278",
url = "conv_1087"
}

Đurović, S., Micić, D., Sorgić, S., Popov, S., Gašić, U., Tosti, T., Kostić, M., Smyatskaya, Y. A., Blagojević, S.,& Zeković, Z.. (2023). Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. in Molecules
MDPI AG., 28(5).
https://doi.org/10.3390/molecules28052278
conv_1087

Đurović S, Micić D, Sorgić S, Popov S, Gašić U, Tosti T, Kostić M, Smyatskaya YA, Blagojević S, Zeković Z. Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts. in Molecules. 2023;28(5).
doi:10.3390/molecules28052278
conv_1087 .

Đurović, Saša, Micić, Darko, Sorgić, Sasa, Popov, Sasa, Gašić, Uroš, Tosti, Tomislav, Kostić, Marija, Smyatskaya, Yulia A., Blagojević, Stevan, Zeković, Zoran, "Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts" in Molecules, 28, no. 5 (2023),
https://doi.org/10.3390/molecules28052278 .,
conv_1087 .

TY  - JOUR
AU  - Đurović, Saša
AU  - Pezo, Lato
AU  - Gašić, Uroš
AU  - Gorjanović, Stanislava
AU  - Pastor, Ferenc T.
AU  - Bazarnova, Julia
AU  - Smyatskaya, Yulia A.
AU  - Zeković, Zoran
PY  - 2023
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/1004
AB  - Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant's popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r(2) value during the training cycle for output variables was 0.999).
PB  - MDPI AG
T2  - Foods
T1  - Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
IS  - 4
VL  - 12
DO  - 10.3390/foods12040809
UR  - conv_1086
ER  - 

@article{
author = "Đurović, Saša and Pezo, Lato and Gašić, Uroš and Gorjanović, Stanislava and Pastor, Ferenc T. and Bazarnova, Julia and Smyatskaya, Yulia A. and Zeković, Zoran",
year = "2023",
abstract = "Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant's popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r(2) value during the training cycle for output variables was 0.999).",
publisher = "MDPI AG",
journal = "Foods",
title = "Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction",
number = "4",
volume = "12",
doi = "10.3390/foods12040809",
url = "conv_1086"
}

Đurović, S., Pezo, L., Gašić, U., Gorjanović, S., Pastor, F. T., Bazarnova, J., Smyatskaya, Y. A.,& Zeković, Z.. (2023). Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction. in Foods
MDPI AG., 12(4).
https://doi.org/10.3390/foods12040809
conv_1086

Đurović S, Pezo L, Gašić U, Gorjanović S, Pastor FT, Bazarnova J, Smyatskaya YA, Zeković Z. Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction. in Foods. 2023;12(4).
doi:10.3390/foods12040809
conv_1086 .

Đurović, Saša, Pezo, Lato, Gašić, Uroš, Gorjanović, Stanislava, Pastor, Ferenc T., Bazarnova, Julia, Smyatskaya, Yulia A., Zeković, Zoran, "Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction" in Foods, 12, no. 4 (2023),
https://doi.org/10.3390/foods12040809 .,
conv_1086 .

TY  - JOUR
AU  - Đurović, Saša
AU  - Sorgić, Sasa
AU  - Popov, Sasa
AU  - Pezo, Lato
AU  - Masković, Pavle
AU  - Blagojević, Stevan
AU  - Zeković, Zoran
PY  - 2022
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/924
AB  - Stinging nettle is annual plant from Urticaceae family used as food and medicine. Due to the nonsufficient data, this work aimed to isolate the bioactive compounds from the stinging nettle leaves by supercritical carbon dioxide. Extracts were analyzed and assessed for antioxidant and cytotoxic activities. Main fatty acids were alpha-linolenic (31.06-58.42 mg/g E), palmitic (9.17-13.12 mg/g E), and linoleic (10.93-16.51 mg/g E) acids. Chlorophylls (33.00-7365.11 mg/100 g E) and carotenoids (166.88-722.62 mg/100 g E) were also found in all samples. Four empirical kinetic equations were effectively utilized for kinetic modeling of supercritical fluid extraction. As per proper statistical features, empirical models show good concurrence with experimental data. The numerical modeling of a process is gainful to foresee the process conduct and furthermore extend the methodology from laboratory to industrial scales. The principal component analysis was used to visualize the fatty acids profile, antioxidant capacity, and cytotoxic activity of extract.
T2  - Food Chemistry
T1  - Recovery of biologically active compounds from stinging nettle leaves part I: Supercritical carbon dioxide extraction
VL  - 373
DO  - 10.1016/j.foodchem.2021.131724
UR  - conv_972
ER  - 

@article{
author = "Đurović, Saša and Sorgić, Sasa and Popov, Sasa and Pezo, Lato and Masković, Pavle and Blagojević, Stevan and Zeković, Zoran",
year = "2022",
abstract = "Stinging nettle is annual plant from Urticaceae family used as food and medicine. Due to the nonsufficient data, this work aimed to isolate the bioactive compounds from the stinging nettle leaves by supercritical carbon dioxide. Extracts were analyzed and assessed for antioxidant and cytotoxic activities. Main fatty acids were alpha-linolenic (31.06-58.42 mg/g E), palmitic (9.17-13.12 mg/g E), and linoleic (10.93-16.51 mg/g E) acids. Chlorophylls (33.00-7365.11 mg/100 g E) and carotenoids (166.88-722.62 mg/100 g E) were also found in all samples. Four empirical kinetic equations were effectively utilized for kinetic modeling of supercritical fluid extraction. As per proper statistical features, empirical models show good concurrence with experimental data. The numerical modeling of a process is gainful to foresee the process conduct and furthermore extend the methodology from laboratory to industrial scales. The principal component analysis was used to visualize the fatty acids profile, antioxidant capacity, and cytotoxic activity of extract.",
journal = "Food Chemistry",
title = "Recovery of biologically active compounds from stinging nettle leaves part I: Supercritical carbon dioxide extraction",
volume = "373",
doi = "10.1016/j.foodchem.2021.131724",
url = "conv_972"
}

Đurović, S., Sorgić, S., Popov, S., Pezo, L., Masković, P., Blagojević, S.,& Zeković, Z.. (2022). Recovery of biologically active compounds from stinging nettle leaves part I: Supercritical carbon dioxide extraction. in Food Chemistry, 373.
https://doi.org/10.1016/j.foodchem.2021.131724
conv_972

Đurović S, Sorgić S, Popov S, Pezo L, Masković P, Blagojević S, Zeković Z. Recovery of biologically active compounds from stinging nettle leaves part I: Supercritical carbon dioxide extraction. in Food Chemistry. 2022;373.
doi:10.1016/j.foodchem.2021.131724
conv_972 .

Đurović, Saša, Sorgić, Sasa, Popov, Sasa, Pezo, Lato, Masković, Pavle, Blagojević, Stevan, Zeković, Zoran, "Recovery of biologically active compounds from stinging nettle leaves part I: Supercritical carbon dioxide extraction" in Food Chemistry, 373 (2022),
https://doi.org/10.1016/j.foodchem.2021.131724 .,
conv_972 .

TY  - JOUR
AU  - Dimić, Ivana
AU  - Pezo, Lato
AU  - Rakić, Dušan
AU  - Teslić, Nemanja
AU  - Zeković, Zoran
AU  - Pavlić, Branimir
PY  - 2021
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/841
AB  - This study was primarily focused on the supercritical fluid extraction (SFE) of cherry seed oil and the optimization of the process using sequential extraction kinetics modeling and artificial neural networks (ANN). The SFE study was organized according to Box-Behnken design of experiment, with additional runs. Pressure, temperature and flow rate were chosen as independent variables. Five well known empirical kinetic models and three mass-transfer kinetics models based on the Sovova's solution of SFE equations were successfully applied for kinetics modeling. The developed mass-transfer models exhibited better fit of experimental data, according to the calculated statistical tests (R-2, SSE and AARD). The initial slope of the SFE curve was evaluated as an output variable in the ANN optimization. The obtained results suggested that it is advisable to lead SFE process at an increased pressure and CO2 flow rate with lower temperature and particle size values to reach a maximal initial slope.
PB  - MDPI AG
T2  - Foods
T1  - Supercritical Fluid Extraction Kinetics of Cherry Seed Oil: Kinetics Modeling and ANN Optimization
IS  - 7
VL  - 10
DO  - 10.3390/foods10071513
UR  - conv_941
ER  - 

@article{
author = "Dimić, Ivana and Pezo, Lato and Rakić, Dušan and Teslić, Nemanja and Zeković, Zoran and Pavlić, Branimir",
year = "2021",
abstract = "This study was primarily focused on the supercritical fluid extraction (SFE) of cherry seed oil and the optimization of the process using sequential extraction kinetics modeling and artificial neural networks (ANN). The SFE study was organized according to Box-Behnken design of experiment, with additional runs. Pressure, temperature and flow rate were chosen as independent variables. Five well known empirical kinetic models and three mass-transfer kinetics models based on the Sovova's solution of SFE equations were successfully applied for kinetics modeling. The developed mass-transfer models exhibited better fit of experimental data, according to the calculated statistical tests (R-2, SSE and AARD). The initial slope of the SFE curve was evaluated as an output variable in the ANN optimization. The obtained results suggested that it is advisable to lead SFE process at an increased pressure and CO2 flow rate with lower temperature and particle size values to reach a maximal initial slope.",
publisher = "MDPI AG",
journal = "Foods",
title = "Supercritical Fluid Extraction Kinetics of Cherry Seed Oil: Kinetics Modeling and ANN Optimization",
number = "7",
volume = "10",
doi = "10.3390/foods10071513",
url = "conv_941"
}

Dimić, I., Pezo, L., Rakić, D., Teslić, N., Zeković, Z.,& Pavlić, B.. (2021). Supercritical Fluid Extraction Kinetics of Cherry Seed Oil: Kinetics Modeling and ANN Optimization. in Foods
MDPI AG., 10(7).
https://doi.org/10.3390/foods10071513
conv_941

Dimić I, Pezo L, Rakić D, Teslić N, Zeković Z, Pavlić B. Supercritical Fluid Extraction Kinetics of Cherry Seed Oil: Kinetics Modeling and ANN Optimization. in Foods. 2021;10(7).
doi:10.3390/foods10071513
conv_941 .

Dimić, Ivana, Pezo, Lato, Rakić, Dušan, Teslić, Nemanja, Zeković, Zoran, Pavlić, Branimir, "Supercritical Fluid Extraction Kinetics of Cherry Seed Oil: Kinetics Modeling and ANN Optimization" in Foods, 10, no. 7 (2021),
https://doi.org/10.3390/foods10071513 .,
conv_941 .

TY  - JOUR
AU  - Pavlić, Branimir
AU  - Teslić, Nemanja
AU  - Zengin, Gokhan
AU  - Đurović, Saša
AU  - Rakić, Dušan
AU  - Cvetanović, Aleksandra
AU  - Gunes, A. K.
AU  - Zeković, Zoran
PY  - 2021
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/851
AB  - Peppermint is widely used medicinal plant with distinguished bioactive potential, therefore, the aim of present work was to develop novel peppermint extracts with high activity by application of traditional and emerging separation techniques. Conventional hydrodistillation and microwave-assisted hydrodistillation (MWHD) were applied for recovery of essential oil (EO), while organic solvent extraction using Soxhlet apparatus, microwave-assisted and ultrasound-assisted process and supercritical fluid extraction (SFE) were applied for non-selective recovery of peppermint lipophilic extracts. Extracts were characterized in terms of terpenoids profile with special emphasis on content of major compounds (mentol, menthone, isomenthol and eucalyptol). Antioxidant activity (DPPH, ABTS, CUPRAC, FRAP, chelating and phosphomolybdenum assay) and enzyme-inhibitory assays (acetylcholinesterase, butyrylcholinesterase, tyrosinase, amylase and glucosidase inhibition) were used for screening of peppermint bioactivity. MWHD was recognized as alternative for traditional process in EO recovery, while SFE extracts were useful for green production of solvent-free peppermint extracts rich in terpenoids and other lipophilic bioactives.
T2  - Food Chemistry
T1  - Antioxidant and enzyme-inhibitory activity of peppermint extracts and essential oils obtained by conventional and emerging extraction techniques
VL  - 338
DO  - 10.1016/j.foodchem.2020.127724
UR  - conv_885
ER  - 

@article{
author = "Pavlić, Branimir and Teslić, Nemanja and Zengin, Gokhan and Đurović, Saša and Rakić, Dušan and Cvetanović, Aleksandra and Gunes, A. K. and Zeković, Zoran",
year = "2021",
abstract = "Peppermint is widely used medicinal plant with distinguished bioactive potential, therefore, the aim of present work was to develop novel peppermint extracts with high activity by application of traditional and emerging separation techniques. Conventional hydrodistillation and microwave-assisted hydrodistillation (MWHD) were applied for recovery of essential oil (EO), while organic solvent extraction using Soxhlet apparatus, microwave-assisted and ultrasound-assisted process and supercritical fluid extraction (SFE) were applied for non-selective recovery of peppermint lipophilic extracts. Extracts were characterized in terms of terpenoids profile with special emphasis on content of major compounds (mentol, menthone, isomenthol and eucalyptol). Antioxidant activity (DPPH, ABTS, CUPRAC, FRAP, chelating and phosphomolybdenum assay) and enzyme-inhibitory assays (acetylcholinesterase, butyrylcholinesterase, tyrosinase, amylase and glucosidase inhibition) were used for screening of peppermint bioactivity. MWHD was recognized as alternative for traditional process in EO recovery, while SFE extracts were useful for green production of solvent-free peppermint extracts rich in terpenoids and other lipophilic bioactives.",
journal = "Food Chemistry",
title = "Antioxidant and enzyme-inhibitory activity of peppermint extracts and essential oils obtained by conventional and emerging extraction techniques",
volume = "338",
doi = "10.1016/j.foodchem.2020.127724",
url = "conv_885"
}

Pavlić, B., Teslić, N., Zengin, G., Đurović, S., Rakić, D., Cvetanović, A., Gunes, A. K.,& Zeković, Z.. (2021). Antioxidant and enzyme-inhibitory activity of peppermint extracts and essential oils obtained by conventional and emerging extraction techniques. in Food Chemistry, 338.
https://doi.org/10.1016/j.foodchem.2020.127724
conv_885

Pavlić B, Teslić N, Zengin G, Đurović S, Rakić D, Cvetanović A, Gunes AK, Zeković Z. Antioxidant and enzyme-inhibitory activity of peppermint extracts and essential oils obtained by conventional and emerging extraction techniques. in Food Chemistry. 2021;338.
doi:10.1016/j.foodchem.2020.127724
conv_885 .

Pavlić, Branimir, Teslić, Nemanja, Zengin, Gokhan, Đurović, Saša, Rakić, Dušan, Cvetanović, Aleksandra, Gunes, A. K., Zeković, Zoran, "Antioxidant and enzyme-inhibitory activity of peppermint extracts and essential oils obtained by conventional and emerging extraction techniques" in Food Chemistry, 338 (2021),
https://doi.org/10.1016/j.foodchem.2020.127724 .,
conv_885 .

TY  - JOUR
AU  - Filip, Snežana
AU  - Đurović, Saša
AU  - Blagojević, Stevan
AU  - Tomić, Ana
AU  - Ranitović, Aleksandra
AU  - Gašić, Uroš
AU  - Tešić, Živoslav
AU  - Zeković, Zoran
PY  - 2021
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/794
AB  - The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra-high-performance liquid chromatography, with a diode array detector coupled with triple-quadrupole mass spectrometer and gas chromatography-mass spectrometry techniques. Thirty-one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5-O-caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram-positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATCC 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties.
PB  - Weinheim: Wiley-VCH Verlag Gmbh
T2  - Archiv der Pharmazie
T1  - Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts
IS  - 2
VL  - 354
DO  - 10.1002/ardp.202000195
UR  - conv_886
ER  - 

@article{
author = "Filip, Snežana and Đurović, Saša and Blagojević, Stevan and Tomić, Ana and Ranitović, Aleksandra and Gašić, Uroš and Tešić, Živoslav and Zeković, Zoran",
year = "2021",
abstract = "The main goal of this study was to establish the chemical profile of Osage orange (Maclura pomifera) leaf extracts, obtained by conventional maceration technique, and to examine its antimicrobial activity. The identification and quantification of the extract compounds were done using ultra-high-performance liquid chromatography, with a diode array detector coupled with triple-quadrupole mass spectrometer and gas chromatography-mass spectrometry techniques. Thirty-one polyphenolic compounds were detected and identified in the ethanolic extracts, whereby 5-O-caffeoylquinic acid was found to be the dominant compound. Among other compounds, pentacosane and palmitic acid were the most abundant compounds in the dichloromethane extract. The preliminary antimicrobial activity screening shows that Gram-positive bacteria tend to be more sensitive to the investigated extracts. The highest antimicrobial activity was determined against Enterococcus faecalis ATCC 19433 and Listeria monocytogenes ATCC 35152. From these results, Osage orange leaves can be considered as plant material with significant antimicrobial properties.",
publisher = "Weinheim: Wiley-VCH Verlag Gmbh",
journal = "Archiv der Pharmazie",
title = "Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts",
number = "2",
volume = "354",
doi = "10.1002/ardp.202000195",
url = "conv_886"
}

Filip, S., Đurović, S., Blagojević, S., Tomić, A., Ranitović, A., Gašić, U., Tešić, Ž.,& Zeković, Z.. (2021). Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts. in Archiv der Pharmazie
Weinheim: Wiley-VCH Verlag Gmbh., 354(2).
https://doi.org/10.1002/ardp.202000195
conv_886

Filip S, Đurović S, Blagojević S, Tomić A, Ranitović A, Gašić U, Tešić Ž, Zeković Z. Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts. in Archiv der Pharmazie. 2021;354(2).
doi:10.1002/ardp.202000195
conv_886 .

Filip, Snežana, Đurović, Saša, Blagojević, Stevan, Tomić, Ana, Ranitović, Aleksandra, Gašić, Uroš, Tešić, Živoslav, Zeković, Zoran, "Chemical composition and antimicrobial activity of Osage orange (Maclura pomifera) leaf extracts" in Archiv der Pharmazie, 354, no. 2 (2021),
https://doi.org/10.1002/ardp.202000195 .,
conv_886 .

TY  - JOUR
AU  - Radivojac, Aleksandar
AU  - Bera, Oskar
AU  - Micić, Darko
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Blagojević, Stevan
AU  - Pavlić, Branimir
PY  - 2020
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/760
AB  - Sage herbal dust generated as a by-product from filter-tea factory contains various bioactive compounds which secured its economic potential towards valorization of under-utilized stream. The aim of this work was to utilize sage herbal dust as raw material for the recovery of value-added product. Comparative evaluation of hydrodistillation (HD) and microwave-assisted hydrodistillation (MWHD) processes applied for isolation of sage herbal dust essential oil (EO) were applied for this purpose and EO yield varied from 0.50 to 1.90%. Distillation experiments performed at different levels of power and kinetics of EO recovery were monitored, while four empirical kinetic equations were successfully applied for modeling of process kinetics according to appropriate values of statistical parameters (R2 and AARD). GC-MS analysis was applied for chemical characterization of sage EOs, while DPPH assay was used to determine in vitro bioactivity and results suggested that power affected terpenoid profile and antioxidant activity in case of HD and MWHD. Thermal analysis of obtained EOs was utilized to establish correlation between thermal behavior and terpenoids profile. Results suggested that MWHD could provide excellent alternative for production of high-quality sage EO with high content of oxygenated terpenoids and adequate bioactivity.
T2  - Food and Bioproducts Processing
T1  - Conventional versus microwave-assisted hydrodistillation of sage herbal dust: Kinetics modeling and physico-chemical properties of essential oil
EP  - 101
SP  - 90
VL  - 123
DO  - 10.1016/j.fbp.2020.06.015
UR  - conv_875
ER  - 

@article{
author = "Radivojac, Aleksandar and Bera, Oskar and Micić, Darko and Đurović, Saša and Zeković, Zoran and Blagojević, Stevan and Pavlić, Branimir",
year = "2020",
abstract = "Sage herbal dust generated as a by-product from filter-tea factory contains various bioactive compounds which secured its economic potential towards valorization of under-utilized stream. The aim of this work was to utilize sage herbal dust as raw material for the recovery of value-added product. Comparative evaluation of hydrodistillation (HD) and microwave-assisted hydrodistillation (MWHD) processes applied for isolation of sage herbal dust essential oil (EO) were applied for this purpose and EO yield varied from 0.50 to 1.90%. Distillation experiments performed at different levels of power and kinetics of EO recovery were monitored, while four empirical kinetic equations were successfully applied for modeling of process kinetics according to appropriate values of statistical parameters (R2 and AARD). GC-MS analysis was applied for chemical characterization of sage EOs, while DPPH assay was used to determine in vitro bioactivity and results suggested that power affected terpenoid profile and antioxidant activity in case of HD and MWHD. Thermal analysis of obtained EOs was utilized to establish correlation between thermal behavior and terpenoids profile. Results suggested that MWHD could provide excellent alternative for production of high-quality sage EO with high content of oxygenated terpenoids and adequate bioactivity.",
journal = "Food and Bioproducts Processing",
title = "Conventional versus microwave-assisted hydrodistillation of sage herbal dust: Kinetics modeling and physico-chemical properties of essential oil",
pages = "101-90",
volume = "123",
doi = "10.1016/j.fbp.2020.06.015",
url = "conv_875"
}

Radivojac, A., Bera, O., Micić, D., Đurović, S., Zeković, Z., Blagojević, S.,& Pavlić, B.. (2020). Conventional versus microwave-assisted hydrodistillation of sage herbal dust: Kinetics modeling and physico-chemical properties of essential oil. in Food and Bioproducts Processing, 123, 90-101.
https://doi.org/10.1016/j.fbp.2020.06.015
conv_875

Radivojac A, Bera O, Micić D, Đurović S, Zeković Z, Blagojević S, Pavlić B. Conventional versus microwave-assisted hydrodistillation of sage herbal dust: Kinetics modeling and physico-chemical properties of essential oil. in Food and Bioproducts Processing. 2020;123:90-101.
doi:10.1016/j.fbp.2020.06.015
conv_875 .

Radivojac, Aleksandar, Bera, Oskar, Micić, Darko, Đurović, Saša, Zeković, Zoran, Blagojević, Stevan, Pavlić, Branimir, "Conventional versus microwave-assisted hydrodistillation of sage herbal dust: Kinetics modeling and physico-chemical properties of essential oil" in Food and Bioproducts Processing, 123 (2020):90-101,
https://doi.org/10.1016/j.fbp.2020.06.015 .,
conv_875 .

TY  - JOUR
AU  - Popov, Sasa
AU  - Skeledzija, Suzana
AU  - Sorgić, Sasa
AU  - Zeković, Zoran
AU  - Micić, Darko
AU  - Radulović, Aleksandra
AU  - Đurović, Saša
PY  - 2020
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/744
AB  - Stinging nettle (Urtica dioica L.) is a perennial plant belonging to the Urticaceae family. Several studies have reported the presence of the different classes of chemical compounds, which expressed a beneficial effect on human health. Among them there are elements and minerals that are essential for the proper functioning of organism. Mineral occurrence requires analytical data about the content. For such purposes was developed and validated a method based on the optical emission spectroscopy coupled with inductively coupled plasma (ICP-OES). Minerals and elements were extracted using two conventional methods (Soxhlet and maceration) and two non-conventional (ultrasound- and microwave-assisted techniques). The extracts were analyzed resulting in high diversity in the composition. Non-conventional techniques showed better results, since those extracts possessed high content of the macroelements and iron as well, instead the toxic elements were found in trace amount
PB  - MDPI AG
T2  - Applied Sciences-Basel
T1  - Application of Contemporary Extraction Techniques for Elements and Minerals Recovery from Stinging Nettle Leaves
IS  - 3
VL  - 10
DO  - 10.3390/app10030793
UR  - conv_837
ER  - 

@article{
author = "Popov, Sasa and Skeledzija, Suzana and Sorgić, Sasa and Zeković, Zoran and Micić, Darko and Radulović, Aleksandra and Đurović, Saša",
year = "2020",
abstract = "Stinging nettle (Urtica dioica L.) is a perennial plant belonging to the Urticaceae family. Several studies have reported the presence of the different classes of chemical compounds, which expressed a beneficial effect on human health. Among them there are elements and minerals that are essential for the proper functioning of organism. Mineral occurrence requires analytical data about the content. For such purposes was developed and validated a method based on the optical emission spectroscopy coupled with inductively coupled plasma (ICP-OES). Minerals and elements were extracted using two conventional methods (Soxhlet and maceration) and two non-conventional (ultrasound- and microwave-assisted techniques). The extracts were analyzed resulting in high diversity in the composition. Non-conventional techniques showed better results, since those extracts possessed high content of the macroelements and iron as well, instead the toxic elements were found in trace amount",
publisher = "MDPI AG",
journal = "Applied Sciences-Basel",
title = "Application of Contemporary Extraction Techniques for Elements and Minerals Recovery from Stinging Nettle Leaves",
number = "3",
volume = "10",
doi = "10.3390/app10030793",
url = "conv_837"
}

Popov, S., Skeledzija, S., Sorgić, S., Zeković, Z., Micić, D., Radulović, A.,& Đurović, S.. (2020). Application of Contemporary Extraction Techniques for Elements and Minerals Recovery from Stinging Nettle Leaves. in Applied Sciences-Basel
MDPI AG., 10(3).
https://doi.org/10.3390/app10030793
conv_837

Popov S, Skeledzija S, Sorgić S, Zeković Z, Micić D, Radulović A, Đurović S. Application of Contemporary Extraction Techniques for Elements and Minerals Recovery from Stinging Nettle Leaves. in Applied Sciences-Basel. 2020;10(3).
doi:10.3390/app10030793
conv_837 .

Popov, Sasa, Skeledzija, Suzana, Sorgić, Sasa, Zeković, Zoran, Micić, Darko, Radulović, Aleksandra, Đurović, Saša, "Application of Contemporary Extraction Techniques for Elements and Minerals Recovery from Stinging Nettle Leaves" in Applied Sciences-Basel, 10, no. 3 (2020),
https://doi.org/10.3390/app10030793 .,
conv_837 .

TY  - JOUR
AU  - Sojić, Branislav
AU  - Pavlić, Branimir
AU  - Tomović, Vladimir
AU  - Kocić-Tanackov, Suncica
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Belović, Miona
AU  - Torbica, Aleksandra
AU  - Jokanović, Marija
AU  - Uromović, Nebojša
AU  - Vujadinović, Dragan
AU  - Ivić, Maja
AU  - Skaljac, Snežana
PY  - 2020
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/751
AB  - The effect of supercritical fluid extract of tomato pomace (TP) and essential oil of organic peppermint (PM) on pH, color, residual nitrite content, lipid oxidation (TBARS value) and total plate count (TPC) of cooked pork sausages produced with 50 mg/kg of sodium nitrite was investigated. Five batches were produced: T1: 100 mgkg of sodium nitrite; T2: 50 mg of sodium nitrite; T3: 50 mg of sodium nitrite and 0.150 mu L/g TP; T4: 50 mg of sodium nitrite, 0.075 mu L/g TP and 0.075 mu L/g PM; T5: 50 mg of sodium nitrite and 0.150 mu L/g PM. The lowest residual nitrite content and TBARS value were observed in treatment T4. The inclusion of TP increased redness of cooked pork sausages. TPC was the lowest in treatment T5. The results of this study showed that the addition of TP and PM enhanced quality of cooked sausages produced with reduced level of sodium nitrite.
T2  - Food Chemistry
T1  - Tomato pomace extract and organic peppermint essential oil as effective sodium nitrite replacement in cooked pork sausages
VL  - 330
DO  - 10.1016/j.foodchem.2020.127202
UR  - conv_854
ER  - 

@article{
author = "Sojić, Branislav and Pavlić, Branimir and Tomović, Vladimir and Kocić-Tanackov, Suncica and Đurović, Saša and Zeković, Zoran and Belović, Miona and Torbica, Aleksandra and Jokanović, Marija and Uromović, Nebojša and Vujadinović, Dragan and Ivić, Maja and Skaljac, Snežana",
year = "2020",
abstract = "The effect of supercritical fluid extract of tomato pomace (TP) and essential oil of organic peppermint (PM) on pH, color, residual nitrite content, lipid oxidation (TBARS value) and total plate count (TPC) of cooked pork sausages produced with 50 mg/kg of sodium nitrite was investigated. Five batches were produced: T1: 100 mgkg of sodium nitrite; T2: 50 mg of sodium nitrite; T3: 50 mg of sodium nitrite and 0.150 mu L/g TP; T4: 50 mg of sodium nitrite, 0.075 mu L/g TP and 0.075 mu L/g PM; T5: 50 mg of sodium nitrite and 0.150 mu L/g PM. The lowest residual nitrite content and TBARS value were observed in treatment T4. The inclusion of TP increased redness of cooked pork sausages. TPC was the lowest in treatment T5. The results of this study showed that the addition of TP and PM enhanced quality of cooked sausages produced with reduced level of sodium nitrite.",
journal = "Food Chemistry",
title = "Tomato pomace extract and organic peppermint essential oil as effective sodium nitrite replacement in cooked pork sausages",
volume = "330",
doi = "10.1016/j.foodchem.2020.127202",
url = "conv_854"
}

Sojić, B., Pavlić, B., Tomović, V., Kocić-Tanackov, S., Đurović, S., Zeković, Z., Belović, M., Torbica, A., Jokanović, M., Uromović, N., Vujadinović, D., Ivić, M.,& Skaljac, S.. (2020). Tomato pomace extract and organic peppermint essential oil as effective sodium nitrite replacement in cooked pork sausages. in Food Chemistry, 330.
https://doi.org/10.1016/j.foodchem.2020.127202
conv_854

Sojić B, Pavlić B, Tomović V, Kocić-Tanackov S, Đurović S, Zeković Z, Belović M, Torbica A, Jokanović M, Uromović N, Vujadinović D, Ivić M, Skaljac S. Tomato pomace extract and organic peppermint essential oil as effective sodium nitrite replacement in cooked pork sausages. in Food Chemistry. 2020;330.
doi:10.1016/j.foodchem.2020.127202
conv_854 .

Sojić, Branislav, Pavlić, Branimir, Tomović, Vladimir, Kocić-Tanackov, Suncica, Đurović, Saša, Zeković, Zoran, Belović, Miona, Torbica, Aleksandra, Jokanović, Marija, Uromović, Nebojša, Vujadinović, Dragan, Ivić, Maja, Skaljac, Snežana, "Tomato pomace extract and organic peppermint essential oil as effective sodium nitrite replacement in cooked pork sausages" in Food Chemistry, 330 (2020),
https://doi.org/10.1016/j.foodchem.2020.127202 .,
conv_854 .

TY  - JOUR
AU  - Pavlić, Branimir
AU  - Pezo, Lato
AU  - Marić, Boško
AU  - Peic Tukuljac, Lidija
AU  - Zeković, Zoran
AU  - Bodroza Solarov, Marija
AU  - Teslić, Nemanja
PY  - 2020
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/750
AB  - The aim of this study was the optimization of supercritical fluid extraction (SFE) of raspberry seed oil. Sequential extraction kinetic modelling and artificial neural networks (ANN) were used for this purpose. SFE was performed according to the broaden Box-Behnken experimental design with pressure, temperature and CO2 flow rate as independent variables, while the influence of particle size on extraction kinetics and adjustable model parameters was additionally evaluated. Five empirical kinetic equations and mass-transfer model proposed by Sovova were utilized for extraction kinetics modelling. According to appropriate statistical parameters (R-2, SSE and AARD), the mass-transfer model exhibited the best fit of experimental data. The initial mass-transfer rate of extraction curve was used as a response variable in ANN optimization. SFE should be performed at elevated pressure and CO2 flow rate, while temperature and particle size should be held at a lower level in order to achieve a maximal initial mass-transfer rate.
T2  - Journal of Supercritical Fluids
T1  - Supercritical fluid extraction of raspberry seed oil: Experiments and modelling
VL  - 157
DO  - 10.1016/j.supflu.2019.104687
UR  - conv_832
ER  - 

@article{
author = "Pavlić, Branimir and Pezo, Lato and Marić, Boško and Peic Tukuljac, Lidija and Zeković, Zoran and Bodroza Solarov, Marija and Teslić, Nemanja",
year = "2020",
abstract = "The aim of this study was the optimization of supercritical fluid extraction (SFE) of raspberry seed oil. Sequential extraction kinetic modelling and artificial neural networks (ANN) were used for this purpose. SFE was performed according to the broaden Box-Behnken experimental design with pressure, temperature and CO2 flow rate as independent variables, while the influence of particle size on extraction kinetics and adjustable model parameters was additionally evaluated. Five empirical kinetic equations and mass-transfer model proposed by Sovova were utilized for extraction kinetics modelling. According to appropriate statistical parameters (R-2, SSE and AARD), the mass-transfer model exhibited the best fit of experimental data. The initial mass-transfer rate of extraction curve was used as a response variable in ANN optimization. SFE should be performed at elevated pressure and CO2 flow rate, while temperature and particle size should be held at a lower level in order to achieve a maximal initial mass-transfer rate.",
journal = "Journal of Supercritical Fluids",
title = "Supercritical fluid extraction of raspberry seed oil: Experiments and modelling",
volume = "157",
doi = "10.1016/j.supflu.2019.104687",
url = "conv_832"
}

Pavlić, B., Pezo, L., Marić, B., Peic Tukuljac, L., Zeković, Z., Bodroza Solarov, M.,& Teslić, N.. (2020). Supercritical fluid extraction of raspberry seed oil: Experiments and modelling. in Journal of Supercritical Fluids, 157.
https://doi.org/10.1016/j.supflu.2019.104687
conv_832

Pavlić B, Pezo L, Marić B, Peic Tukuljac L, Zeković Z, Bodroza Solarov M, Teslić N. Supercritical fluid extraction of raspberry seed oil: Experiments and modelling. in Journal of Supercritical Fluids. 2020;157.
doi:10.1016/j.supflu.2019.104687
conv_832 .

Pavlić, Branimir, Pezo, Lato, Marić, Boško, Peic Tukuljac, Lidija, Zeković, Zoran, Bodroza Solarov, Marija, Teslić, Nemanja, "Supercritical fluid extraction of raspberry seed oil: Experiments and modelling" in Journal of Supercritical Fluids, 157 (2020),
https://doi.org/10.1016/j.supflu.2019.104687 .,
conv_832 .

TY  - JOUR
AU  - Đurović, Saša
AU  - Vujanović, Milena
AU  - Radojkovc, Marija
AU  - Filipović, Jelena
AU  - Filipović, Vladimir
AU  - Gašić, Uroš
AU  - Tešić, Živoslav
AU  - Masković, Pavle
AU  - Zeković, Zoran
PY  - 2020
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/747
AB  - Stinging nettle is an annual plant. This plant is known for applications in folk medicine, and as the human diet. The stinging nettle leaves has been used to obtain extracts, which are expected to be with a high content of biologically active compounds. Prepared microwave extracts were applied in the formulation of the functional products. The article completes preparation of the bread with addition of the stinging nettle leaves and its extract, and bread's composition in phenolic acids, flavonoids, micro elements, and macro elements. The biological activity of the prepared bread samples showed significant antioxidant activity. This was especially true against DPPH radicals. It has been shown that it holds a high cytotoxic activity. Leaves themselves decreased the quality of the bread, while the extract improved the quality. It was sensorially confirmed. The article concluded that the extract substitutes leaves in bread as a product of a high benefit.
PB  - Elsevier Ltd
T2  - Food Chemistry
T1  - The functional food production: Application of stinging nettle leaves and its extracts in the baking of a bread
VL  - 312
DO  - 10.1016/j.foodchem.2019.126091
UR  - conv_824
ER  - 

@article{
author = "Đurović, Saša and Vujanović, Milena and Radojkovc, Marija and Filipović, Jelena and Filipović, Vladimir and Gašić, Uroš and Tešić, Živoslav and Masković, Pavle and Zeković, Zoran",
year = "2020",
abstract = "Stinging nettle is an annual plant. This plant is known for applications in folk medicine, and as the human diet. The stinging nettle leaves has been used to obtain extracts, which are expected to be with a high content of biologically active compounds. Prepared microwave extracts were applied in the formulation of the functional products. The article completes preparation of the bread with addition of the stinging nettle leaves and its extract, and bread's composition in phenolic acids, flavonoids, micro elements, and macro elements. The biological activity of the prepared bread samples showed significant antioxidant activity. This was especially true against DPPH radicals. It has been shown that it holds a high cytotoxic activity. Leaves themselves decreased the quality of the bread, while the extract improved the quality. It was sensorially confirmed. The article concluded that the extract substitutes leaves in bread as a product of a high benefit.",
publisher = "Elsevier Ltd",
journal = "Food Chemistry",
title = "The functional food production: Application of stinging nettle leaves and its extracts in the baking of a bread",
volume = "312",
doi = "10.1016/j.foodchem.2019.126091",
url = "conv_824"
}

Đurović, S., Vujanović, M., Radojkovc, M., Filipović, J., Filipović, V., Gašić, U., Tešić, Ž., Masković, P.,& Zeković, Z.. (2020). The functional food production: Application of stinging nettle leaves and its extracts in the baking of a bread. in Food Chemistry
Elsevier Ltd., 312.
https://doi.org/10.1016/j.foodchem.2019.126091
conv_824

Đurović S, Vujanović M, Radojkovc M, Filipović J, Filipović V, Gašić U, Tešić Ž, Masković P, Zeković Z. The functional food production: Application of stinging nettle leaves and its extracts in the baking of a bread. in Food Chemistry. 2020;312.
doi:10.1016/j.foodchem.2019.126091
conv_824 .

Đurović, Saša, Vujanović, Milena, Radojkovc, Marija, Filipović, Jelena, Filipović, Vladimir, Gašić, Uroš, Tešić, Živoslav, Masković, Pavle, Zeković, Zoran, "The functional food production: Application of stinging nettle leaves and its extracts in the baking of a bread" in Food Chemistry, 312 (2020),
https://doi.org/10.1016/j.foodchem.2019.126091 .,
conv_824 .

TY  - JOUR
AU  - Micić, Darko
AU  - Ostojić, Sanja
AU  - Pezo, Lato
AU  - Blagojević, Stevan
AU  - Pavlić, Branimir
AU  - Zeković, Zoran
AU  - Đurović, Saša
PY  - 2019
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/672
AB  - Essential oils (EOs) are aromatic oily liquids prepared from plant material. Many plants are rich in EOs, which usually consisted of different secondary metabolites such as terpenoids. The EOs or their components have been shown to exhibit antioxidant, antimicrobial, antiviral, antimycotic, antitoxigenic, antiparasitic and insecticidal properties, which is main reason for their ivenstigation. Coriander and sage essential oils, isolated by hydrodistillation, were analyzed using gas chromatography, differential scanning calorimetry and thermogravimetry techniques in order to correlate chemical composition and thermal behavior. Results showed that evaporation process of sage EO takes place in two steps, while coriander EO was evaporated in one step. The activation energy of the evaporation process of both EOs was in accordance to the evaporation enthalpy of dominant compounds in analyzed samples. The quantitative structure-retention relationship (QSRR) was employed to predict the retention time (RT) of essential oil compounds obtained by GC analysis, using five molecular descriptors selected by genetic algorithm. The selected descriptors were used as inputs of an artificial neural network (ANN), to build an RT predictive QSRR model. The coefficient of determination was 0.969, indicating that this model could be used for prediction of RT values for coriander and sage essential oil compounds.
T2  - Industrial Crops and Products
T1  - Essential oils of coriander and sage: Investigation of chemical profile, thermal properties and QSRR analysis
VL  - 138
DO  - 10.1016/j.indcrop.2019.06.001
UR  - conv_795
ER  - 

@article{
author = "Micić, Darko and Ostojić, Sanja and Pezo, Lato and Blagojević, Stevan and Pavlić, Branimir and Zeković, Zoran and Đurović, Saša",
year = "2019",
abstract = "Essential oils (EOs) are aromatic oily liquids prepared from plant material. Many plants are rich in EOs, which usually consisted of different secondary metabolites such as terpenoids. The EOs or their components have been shown to exhibit antioxidant, antimicrobial, antiviral, antimycotic, antitoxigenic, antiparasitic and insecticidal properties, which is main reason for their ivenstigation. Coriander and sage essential oils, isolated by hydrodistillation, were analyzed using gas chromatography, differential scanning calorimetry and thermogravimetry techniques in order to correlate chemical composition and thermal behavior. Results showed that evaporation process of sage EO takes place in two steps, while coriander EO was evaporated in one step. The activation energy of the evaporation process of both EOs was in accordance to the evaporation enthalpy of dominant compounds in analyzed samples. The quantitative structure-retention relationship (QSRR) was employed to predict the retention time (RT) of essential oil compounds obtained by GC analysis, using five molecular descriptors selected by genetic algorithm. The selected descriptors were used as inputs of an artificial neural network (ANN), to build an RT predictive QSRR model. The coefficient of determination was 0.969, indicating that this model could be used for prediction of RT values for coriander and sage essential oil compounds.",
journal = "Industrial Crops and Products",
title = "Essential oils of coriander and sage: Investigation of chemical profile, thermal properties and QSRR analysis",
volume = "138",
doi = "10.1016/j.indcrop.2019.06.001",
url = "conv_795"
}

Micić, D., Ostojić, S., Pezo, L., Blagojević, S., Pavlić, B., Zeković, Z.,& Đurović, S.. (2019). Essential oils of coriander and sage: Investigation of chemical profile, thermal properties and QSRR analysis. in Industrial Crops and Products, 138.
https://doi.org/10.1016/j.indcrop.2019.06.001
conv_795

Micić D, Ostojić S, Pezo L, Blagojević S, Pavlić B, Zeković Z, Đurović S. Essential oils of coriander and sage: Investigation of chemical profile, thermal properties and QSRR analysis. in Industrial Crops and Products. 2019;138.
doi:10.1016/j.indcrop.2019.06.001
conv_795 .

Micić, Darko, Ostojić, Sanja, Pezo, Lato, Blagojević, Stevan, Pavlić, Branimir, Zeković, Zoran, Đurović, Saša, "Essential oils of coriander and sage: Investigation of chemical profile, thermal properties and QSRR analysis" in Industrial Crops and Products, 138 (2019),
https://doi.org/10.1016/j.indcrop.2019.06.001 .,
conv_795 .

TY  - JOUR
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Zeković, Zoran
AU  - Jerković, Jelena
AU  - Zengin, Gokhan
AU  - Gašić, Uroš
AU  - Tešić, Živoslav
AU  - Masković, Pavle
AU  - Soares, Cristina
AU  - Fatima Barroso, M.
AU  - Delerue-Matos, Cristina
AU  - Đurović, Saša
PY  - 2019
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/700
AB  - The main goal of this research was to determine the relationship among chemical structure, bioactivity and temperature of chamomile during subcritical water extraction in isobaric conditions (45 bar) at seven different temperatures (65-210 degrees C). The influence of temperature on phenolic profiles was defined by UHPLC-HESI-MS/MS. The overall results indicate that the presence of conjugated double bonds, side chains, glucose moiety or ether moiety in molecules influence the efficiency of polyphenols' extraction in subcritical water. In terms of antioxidant activity, the extracts were the most active towards ABTS radicals (IC50 = 7.3-16.8 mu g/mL), whereby temperature of 150 degrees C was optimal. On the other hand, the extracts obtained at 115 degrees C showed highest cytotoxicity. Inhibition of alpha-amylase and alpha-glucosidase was the highest at 65 and 85 degrees C, i.e. 0.51 and 4.13 mmolAE/g, respectively. Activity against tyrosinase was the highest at 210 degrees C (17.92 mgKAE/g). The data showed that different non-phenolic compounds may also participate in bio-activities of the extracts.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts
EP  - 337
SP  - 328
VL  - 271
DO  - 10.1016/j.foodchem.2018.07.154
UR  - conv_745
ER  - 

@article{
author = "Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Zeković, Zoran and Jerković, Jelena and Zengin, Gokhan and Gašić, Uroš and Tešić, Živoslav and Masković, Pavle and Soares, Cristina and Fatima Barroso, M. and Delerue-Matos, Cristina and Đurović, Saša",
year = "2019",
abstract = "The main goal of this research was to determine the relationship among chemical structure, bioactivity and temperature of chamomile during subcritical water extraction in isobaric conditions (45 bar) at seven different temperatures (65-210 degrees C). The influence of temperature on phenolic profiles was defined by UHPLC-HESI-MS/MS. The overall results indicate that the presence of conjugated double bonds, side chains, glucose moiety or ether moiety in molecules influence the efficiency of polyphenols' extraction in subcritical water. In terms of antioxidant activity, the extracts were the most active towards ABTS radicals (IC50 = 7.3-16.8 mu g/mL), whereby temperature of 150 degrees C was optimal. On the other hand, the extracts obtained at 115 degrees C showed highest cytotoxicity. Inhibition of alpha-amylase and alpha-glucosidase was the highest at 65 and 85 degrees C, i.e. 0.51 and 4.13 mmolAE/g, respectively. Activity against tyrosinase was the highest at 210 degrees C (17.92 mgKAE/g). The data showed that different non-phenolic compounds may also participate in bio-activities of the extracts.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts",
pages = "337-328",
volume = "271",
doi = "10.1016/j.foodchem.2018.07.154",
url = "conv_745"
}

Cvetanović, A., Svarc-Gajić, J., Zeković, Z., Jerković, J., Zengin, G., Gašić, U., Tešić, Ž., Masković, P., Soares, C., Fatima Barroso, M., Delerue-Matos, C.,& Đurović, S.. (2019). The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts. in Food Chemistry
Elsevier Sci Ltd, Oxford., 271, 328-337.
https://doi.org/10.1016/j.foodchem.2018.07.154
conv_745

Cvetanović A, Svarc-Gajić J, Zeković Z, Jerković J, Zengin G, Gašić U, Tešić Ž, Masković P, Soares C, Fatima Barroso M, Delerue-Matos C, Đurović S. The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts. in Food Chemistry. 2019;271:328-337.
doi:10.1016/j.foodchem.2018.07.154
conv_745 .

Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Zeković, Zoran, Jerković, Jelena, Zengin, Gokhan, Gašić, Uroš, Tešić, Živoslav, Masković, Pavle, Soares, Cristina, Fatima Barroso, M., Delerue-Matos, Cristina, Đurović, Saša, "The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts" in Food Chemistry, 271 (2019):328-337,
https://doi.org/10.1016/j.foodchem.2018.07.154 .,
conv_745 .

TY  - JOUR
AU  - Sojić, Branislav
AU  - Pavlić, Branimir
AU  - Tomović, Vladimir
AU  - Ikonić, Predrag
AU  - Zeković, Zoran
AU  - Kocić-Tanackov, Suncica
AU  - Đurović, Saša
AU  - Skaljac, Snežana
AU  - Jokanović, Marija
AU  - Ivić, Maja
PY  - 2019
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/685
AB  - The effect of winter savory (Satureja montana L.) essential oil (SEO) and supercritical extracts (SE1; SE2) at concentrations of 0.075 and 0.150 mu L/g on pH, lipid oxidation (TBARS), microbial growth and sensory quality of fresh pork sausages during storage were investigated. SEO, SE1 and SE2 improved oxidative and microbial stability of fresh pork sausages. The addition of SEO and SE1 at concentration of 0.150 mu L/g affected the reduction of total Enterobacteriaeceae count to under 3 log cfu/g. Sausages produced with SE1 and SE2 had a higher scores for odor, flavor and overall acceptance compared to sausages treated with SEO and control sample. Therefore, the results of this paper revealed significant antioxidative and antimicrobial activity of SE1 and SE2, and consequently its high potential of utilization in processing of fresh pork sausages.
T2  - Food Chemistry
T1  - Essential oil versus supercritical fluid extracts of winter savory (Satureja montana L.) - Assessment of the oxidative, microbiological and sensory quality of fresh pork sausages
EP  - 286
SP  - 280
VL  - 287
DO  - 10.1016/j.foodchem.2018.12.137
UR  - conv_766
ER  - 

@article{
author = "Sojić, Branislav and Pavlić, Branimir and Tomović, Vladimir and Ikonić, Predrag and Zeković, Zoran and Kocić-Tanackov, Suncica and Đurović, Saša and Skaljac, Snežana and Jokanović, Marija and Ivić, Maja",
year = "2019",
abstract = "The effect of winter savory (Satureja montana L.) essential oil (SEO) and supercritical extracts (SE1; SE2) at concentrations of 0.075 and 0.150 mu L/g on pH, lipid oxidation (TBARS), microbial growth and sensory quality of fresh pork sausages during storage were investigated. SEO, SE1 and SE2 improved oxidative and microbial stability of fresh pork sausages. The addition of SEO and SE1 at concentration of 0.150 mu L/g affected the reduction of total Enterobacteriaeceae count to under 3 log cfu/g. Sausages produced with SE1 and SE2 had a higher scores for odor, flavor and overall acceptance compared to sausages treated with SEO and control sample. Therefore, the results of this paper revealed significant antioxidative and antimicrobial activity of SE1 and SE2, and consequently its high potential of utilization in processing of fresh pork sausages.",
journal = "Food Chemistry",
title = "Essential oil versus supercritical fluid extracts of winter savory (Satureja montana L.) - Assessment of the oxidative, microbiological and sensory quality of fresh pork sausages",
pages = "286-280",
volume = "287",
doi = "10.1016/j.foodchem.2018.12.137",
url = "conv_766"
}

Sojić, B., Pavlić, B., Tomović, V., Ikonić, P., Zeković, Z., Kocić-Tanackov, S., Đurović, S., Skaljac, S., Jokanović, M.,& Ivić, M.. (2019). Essential oil versus supercritical fluid extracts of winter savory (Satureja montana L.) - Assessment of the oxidative, microbiological and sensory quality of fresh pork sausages. in Food Chemistry, 287, 280-286.
https://doi.org/10.1016/j.foodchem.2018.12.137
conv_766

Sojić B, Pavlić B, Tomović V, Ikonić P, Zeković Z, Kocić-Tanackov S, Đurović S, Skaljac S, Jokanović M, Ivić M. Essential oil versus supercritical fluid extracts of winter savory (Satureja montana L.) - Assessment of the oxidative, microbiological and sensory quality of fresh pork sausages. in Food Chemistry. 2019;287:280-286.
doi:10.1016/j.foodchem.2018.12.137
conv_766 .

Sojić, Branislav, Pavlić, Branimir, Tomović, Vladimir, Ikonić, Predrag, Zeković, Zoran, Kocić-Tanackov, Suncica, Đurović, Saša, Skaljac, Snežana, Jokanović, Marija, Ivić, Maja, "Essential oil versus supercritical fluid extracts of winter savory (Satureja montana L.) - Assessment of the oxidative, microbiological and sensory quality of fresh pork sausages" in Food Chemistry, 287 (2019):280-286,
https://doi.org/10.1016/j.foodchem.2018.12.137 .,
conv_766 .

TY  - JOUR
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Sorgić, Sasa
AU  - Popov, Sasa
AU  - Vujanović, Milena
AU  - Radojković, Marija
PY  - 2018
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/605
AB  - Stinging nettle is a perennial plant with significant biological activity and a long history of application in folk medicine and as food. Its activity is ascribed to its chemical composition. Its leaves contain different classes of compounds including fatty acids. This study deals with the isolation of fatty acids in stinging nettle leaves using a rapid extraction system for solid-liquid extraction (Soxtherm) with petroleum ether as the solvent. The obtained results indicate that the saturated fatty acids are more abundant than unsaturated fatty acids. The most abundant fatty acids are C12:0 (20.94%, 348.07 g g(-1)), C16:0 (18.57%, 309.06 g g(-1)), and C18:1 (13.16%, 219.44 g g(-1)), whereas the fatty acid with the lowest content is C17:1 (0.13%, 2.20 g g(-1)). Prior to analysis, the method is validated to obtain accurate and precise results. The limit of detection and limit of quantification are 0.012-0.038% and 1.67-7.03%, whereas the precision and accuracy are 83-126% and 1.67-7.03%, respectively. The validation parameters are >0.999, 0.011-0.032%, 0.012-0.038%, 1.67-7.03%, 83-126%, 0.22-5.24%, and 0.38-6.94% for linearity, limit of detection, limit of quantitation, precision, accuracy, inter-day precision, and intra-day precision, respectively, confirming the suitability of this method for fatty acid analysis.
T2  - Analytical Methods
T1  - Fatty acid profile of stinging nettle leaves: application of modern analytical procedures for sample preparation and analysis
EP  - 1087
IS  - 9
SP  - 1080
VL  - 10
DO  - 10.1039/c7ay02559a
UR  - conv_710
ER  - 

@article{
author = "Đurović, Saša and Zeković, Zoran and Sorgić, Sasa and Popov, Sasa and Vujanović, Milena and Radojković, Marija",
year = "2018",
abstract = "Stinging nettle is a perennial plant with significant biological activity and a long history of application in folk medicine and as food. Its activity is ascribed to its chemical composition. Its leaves contain different classes of compounds including fatty acids. This study deals with the isolation of fatty acids in stinging nettle leaves using a rapid extraction system for solid-liquid extraction (Soxtherm) with petroleum ether as the solvent. The obtained results indicate that the saturated fatty acids are more abundant than unsaturated fatty acids. The most abundant fatty acids are C12:0 (20.94%, 348.07 g g(-1)), C16:0 (18.57%, 309.06 g g(-1)), and C18:1 (13.16%, 219.44 g g(-1)), whereas the fatty acid with the lowest content is C17:1 (0.13%, 2.20 g g(-1)). Prior to analysis, the method is validated to obtain accurate and precise results. The limit of detection and limit of quantification are 0.012-0.038% and 1.67-7.03%, whereas the precision and accuracy are 83-126% and 1.67-7.03%, respectively. The validation parameters are >0.999, 0.011-0.032%, 0.012-0.038%, 1.67-7.03%, 83-126%, 0.22-5.24%, and 0.38-6.94% for linearity, limit of detection, limit of quantitation, precision, accuracy, inter-day precision, and intra-day precision, respectively, confirming the suitability of this method for fatty acid analysis.",
journal = "Analytical Methods",
title = "Fatty acid profile of stinging nettle leaves: application of modern analytical procedures for sample preparation and analysis",
pages = "1087-1080",
number = "9",
volume = "10",
doi = "10.1039/c7ay02559a",
url = "conv_710"
}

Đurović, S., Zeković, Z., Sorgić, S., Popov, S., Vujanović, M.,& Radojković, M.. (2018). Fatty acid profile of stinging nettle leaves: application of modern analytical procedures for sample preparation and analysis. in Analytical Methods, 10(9), 1080-1087.
https://doi.org/10.1039/c7ay02559a
conv_710

Đurović S, Zeković Z, Sorgić S, Popov S, Vujanović M, Radojković M. Fatty acid profile of stinging nettle leaves: application of modern analytical procedures for sample preparation and analysis. in Analytical Methods. 2018;10(9):1080-1087.
doi:10.1039/c7ay02559a
conv_710 .

Đurović, Saša, Zeković, Zoran, Sorgić, Sasa, Popov, Sasa, Vujanović, Milena, Radojković, Marija, "Fatty acid profile of stinging nettle leaves: application of modern analytical procedures for sample preparation and analysis" in Analytical Methods, 10, no. 9 (2018):1080-1087,
https://doi.org/10.1039/c7ay02559a .,
conv_710 .

TY  - JOUR
AU  - Masković, Pavle
AU  - Veličković, Vesna
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Radojković, Marija
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Mitić, Milan
AU  - Vujić, Jelena
PY  - 2018
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/604
AB  - Background: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. Purpose: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. Study design and methods: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. Results and conclusion: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.
T2  - Phytomedicine
T1  - Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches
EP  - 124
SP  - 118
VL  - 38
DO  - 10.1016/j.phymed.2017.11.010
UR  - conv_708
ER  - 

@article{
author = "Masković, Pavle and Veličković, Vesna and Đurović, Saša and Zeković, Zoran and Radojković, Marija and Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Mitić, Milan and Vujić, Jelena",
year = "2018",
abstract = "Background: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. Purpose: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. Study design and methods: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. Results and conclusion: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.",
journal = "Phytomedicine",
title = "Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches",
pages = "124-118",
volume = "38",
doi = "10.1016/j.phymed.2017.11.010",
url = "conv_708"
}

Masković, P., Veličković, V., Đurović, S., Zeković, Z., Radojković, M., Cvetanović, A., Svarc-Gajić, J., Mitić, M.,& Vujić, J.. (2018). Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches. in Phytomedicine, 38, 118-124.
https://doi.org/10.1016/j.phymed.2017.11.010
conv_708

Masković P, Veličković V, Đurović S, Zeković Z, Radojković M, Cvetanović A, Svarc-Gajić J, Mitić M, Vujić J. Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches. in Phytomedicine. 2018;38:118-124.
doi:10.1016/j.phymed.2017.11.010
conv_708 .

Masković, Pavle, Veličković, Vesna, Đurović, Saša, Zeković, Zoran, Radojković, Marija, Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Mitić, Milan, Vujić, Jelena, "Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches" in Phytomedicine, 38 (2018):118-124,
https://doi.org/10.1016/j.phymed.2017.11.010 .,
conv_708 .

TY  - JOUR
AU  - Uysal, Sengul
AU  - Cvetanović, Aleksandra
AU  - Zengin, Gokhan
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Aktumsek, Abdurrahman
PY  - 2018
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/597
AB  - In the last few years, bioactive components or their extraction techniques are gaining special interest in scientific areas. In this framework, orange leaves were used for preparation of extracts with high content of biologically active compounds. To optimize the extraction process, three levels and three variables of Box-Behnken design with response surface methodology were applied. Investigated responses were the total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, cupric ion reducing antioxidant capacity (CUPRAC), and ferric reducing antioxidant power (FRAP). Independent variables were methanol concentration (10-90%), temperature (20-60 degrees C), and extraction time (60-180min). Experimentally obtained results were fit into a second-order polynomial model with multiple regression. Analysis of variance was used to estimate model fitness and determine optimal conditions for processing. Estimated optimal conditions were 90% methanolic solution, 60 degrees C and 180min using these parameters; the predicted values of investigated responses were 43.19mg GAE/g (GAE: gallic acid equivalents), 43.04mg TE/g (TE: trolox equivalents), 139.34 and 93.76mg TE/g for TPC, DPPH, CUPRAC, and FRAP, respectively. The obtained optimal conditions could be considered as an alternative strategy for developing novel functional products.
T2  - Analytical Letters
T1  - Effects of Orange Leaves Extraction Conditions on Antioxidant and Phenolic Content: Optimization Using Response Surface Methodology
EP  - 1519
IS  - 10
SP  - 1505
VL  - 51
DO  - 10.1080/00032719.2017.1382501
UR  - conv_715
ER  - 

@article{
author = "Uysal, Sengul and Cvetanović, Aleksandra and Zengin, Gokhan and Đurović, Saša and Zeković, Zoran and Aktumsek, Abdurrahman",
year = "2018",
abstract = "In the last few years, bioactive components or their extraction techniques are gaining special interest in scientific areas. In this framework, orange leaves were used for preparation of extracts with high content of biologically active compounds. To optimize the extraction process, three levels and three variables of Box-Behnken design with response surface methodology were applied. Investigated responses were the total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, cupric ion reducing antioxidant capacity (CUPRAC), and ferric reducing antioxidant power (FRAP). Independent variables were methanol concentration (10-90%), temperature (20-60 degrees C), and extraction time (60-180min). Experimentally obtained results were fit into a second-order polynomial model with multiple regression. Analysis of variance was used to estimate model fitness and determine optimal conditions for processing. Estimated optimal conditions were 90% methanolic solution, 60 degrees C and 180min using these parameters; the predicted values of investigated responses were 43.19mg GAE/g (GAE: gallic acid equivalents), 43.04mg TE/g (TE: trolox equivalents), 139.34 and 93.76mg TE/g for TPC, DPPH, CUPRAC, and FRAP, respectively. The obtained optimal conditions could be considered as an alternative strategy for developing novel functional products.",
journal = "Analytical Letters",
title = "Effects of Orange Leaves Extraction Conditions on Antioxidant and Phenolic Content: Optimization Using Response Surface Methodology",
pages = "1519-1505",
number = "10",
volume = "51",
doi = "10.1080/00032719.2017.1382501",
url = "conv_715"
}

Uysal, S., Cvetanović, A., Zengin, G., Đurović, S., Zeković, Z.,& Aktumsek, A.. (2018). Effects of Orange Leaves Extraction Conditions on Antioxidant and Phenolic Content: Optimization Using Response Surface Methodology. in Analytical Letters, 51(10), 1505-1519.
https://doi.org/10.1080/00032719.2017.1382501
conv_715

Uysal S, Cvetanović A, Zengin G, Đurović S, Zeković Z, Aktumsek A. Effects of Orange Leaves Extraction Conditions on Antioxidant and Phenolic Content: Optimization Using Response Surface Methodology. in Analytical Letters. 2018;51(10):1505-1519.
doi:10.1080/00032719.2017.1382501
conv_715 .

Uysal, Sengul, Cvetanović, Aleksandra, Zengin, Gokhan, Đurović, Saša, Zeković, Zoran, Aktumsek, Abdurrahman, "Effects of Orange Leaves Extraction Conditions on Antioxidant and Phenolic Content: Optimization Using Response Surface Methodology" in Analytical Letters, 51, no. 10 (2018):1505-1519,
https://doi.org/10.1080/00032719.2017.1382501 .,
conv_715 .

TY  - JOUR
AU  - Masković, Pavle
AU  - Radojković, Marija
AU  - Cvetanović, Aleksandra
AU  - Mitić, Milan
AU  - Zeković, Zoran
AU  - Đurović, Saša
PY  - 2018
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/585
AB  - Fruits of Prunus cerasus L. (tart cherry) represent a significant source of health beneficial compounds and have been widely used in food industry. Despite that, other plant parts, such as twigs, have not been investigated. Aim of this study was to investigate chemical profile of twig extracts prepared from plant material of three cultivars. Wig extracts were prepared using maceration and Soxhlet extraction approaches, and investigated regarding phenolics (5.85-14.80 mg.l(-1)) and saccharides (123.38-339.46 g.l(-1)) concentrations using high performance liquid chromatography (HPLC) analysis. Total phenolics (99.34-139.77 g.kg(-1)), flavonoids (14.18-42.88 g.kg(-1)), anthocyanins (76.71-84.97 g.kg(-1)), condensed tannins (52.65-79.76 g.kg(-1)) and gallotannins (19.03-37.23 g.kg(-1)) contents were determined using spectrophotometric analysis. Biological activity was investigated using four antioxidant assays (total antioxidant capacity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, lipid peroxidation assay and hydroxyl radical-scavenging activity). Cytotoxic activity was assessed on three different cell lines (Hep2c, RD and L2OB), while antimicrobial activity was established on 15 bacterial strains. Obtained results confirmed the presence of health beneficial compounds in twigs and indicated the possibility of utilization as a secondary source of those compounds.
PB  - Food Reseach Institute
T2  - Journal of Food and Nutrition Research
T1  - Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization
EP  - 230
IS  - 3
SP  - 222
VL  - 57
UR  - conv_1196
ER  - 

@article{
author = "Masković, Pavle and Radojković, Marija and Cvetanović, Aleksandra and Mitić, Milan and Zeković, Zoran and Đurović, Saša",
year = "2018",
abstract = "Fruits of Prunus cerasus L. (tart cherry) represent a significant source of health beneficial compounds and have been widely used in food industry. Despite that, other plant parts, such as twigs, have not been investigated. Aim of this study was to investigate chemical profile of twig extracts prepared from plant material of three cultivars. Wig extracts were prepared using maceration and Soxhlet extraction approaches, and investigated regarding phenolics (5.85-14.80 mg.l(-1)) and saccharides (123.38-339.46 g.l(-1)) concentrations using high performance liquid chromatography (HPLC) analysis. Total phenolics (99.34-139.77 g.kg(-1)), flavonoids (14.18-42.88 g.kg(-1)), anthocyanins (76.71-84.97 g.kg(-1)), condensed tannins (52.65-79.76 g.kg(-1)) and gallotannins (19.03-37.23 g.kg(-1)) contents were determined using spectrophotometric analysis. Biological activity was investigated using four antioxidant assays (total antioxidant capacity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, lipid peroxidation assay and hydroxyl radical-scavenging activity). Cytotoxic activity was assessed on three different cell lines (Hep2c, RD and L2OB), while antimicrobial activity was established on 15 bacterial strains. Obtained results confirmed the presence of health beneficial compounds in twigs and indicated the possibility of utilization as a secondary source of those compounds.",
publisher = "Food Reseach Institute",
journal = "Journal of Food and Nutrition Research",
title = "Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization",
pages = "230-222",
number = "3",
volume = "57",
url = "conv_1196"
}

Masković, P., Radojković, M., Cvetanović, A., Mitić, M., Zeković, Z.,& Đurović, S.. (2018). Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization. in Journal of Food and Nutrition Research
Food Reseach Institute., 57(3), 222-230.
conv_1196

Masković P, Radojković M, Cvetanović A, Mitić M, Zeković Z, Đurović S. Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization. in Journal of Food and Nutrition Research. 2018;57(3):222-230.
conv_1196 .

Masković, Pavle, Radojković, Marija, Cvetanović, Aleksandra, Mitić, Milan, Zeković, Zoran, Đurović, Saša, "Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization" in Journal of Food and Nutrition Research, 57, no. 3 (2018):222-230,
conv_1196 .

TY  - JOUR
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Zeković, Zoran
AU  - Gašić, Uroš
AU  - Tešić, Živoslav
AU  - Zengin, Gokhan
AU  - Masković, Pavle
AU  - Mahomoodally, Mohamad Fawzi
AU  - Đurović, Saša
PY  - 2018
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/579
AB  - The study was designed to determine the relationship between chemical structure, bioactivity and pressure during the subcritical water extraction (SCW) of chamomile. Extraction was carried out at isothermal conditions (100 degrees C) at five different pressures (10, 30, 45, 60 and 90 bar). Twenty three polyphenolic compounds were identified in the extracts, whereby apigenin was found to be the dominant compound (61.53-1344.99 mg/kg). Results suggest that the lowest applied pressure has negligible effect on phenolic recovery from chamomile, but also the use of pressures above than 45 bar was proven as needlessly. By using in vitro assays, influence of pressure on antioxidant, cytotoxic and enzyme-inhibitory activities of the extracts was evaluated. Extracts obtained at 30, 45 and 60 bar exhibited stronger bioactivities than at 10 and 90 bar. It was concluded that pressure exert a significant influence on chemical composition of extracts, and thus on biological activity of chamomile extracts.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Subcritical water extraction as a cutting edge technology for the extraction of bioactive compounds from chamomile: Influence of pressure on chemical composition and bioactivity of extracts
EP  - 396
SP  - 389
VL  - 266
DO  - 10.1016/j.foodchem.2018.06.037
UR  - conv_730
ER  - 

@article{
author = "Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Zeković, Zoran and Gašić, Uroš and Tešić, Živoslav and Zengin, Gokhan and Masković, Pavle and Mahomoodally, Mohamad Fawzi and Đurović, Saša",
year = "2018",
abstract = "The study was designed to determine the relationship between chemical structure, bioactivity and pressure during the subcritical water extraction (SCW) of chamomile. Extraction was carried out at isothermal conditions (100 degrees C) at five different pressures (10, 30, 45, 60 and 90 bar). Twenty three polyphenolic compounds were identified in the extracts, whereby apigenin was found to be the dominant compound (61.53-1344.99 mg/kg). Results suggest that the lowest applied pressure has negligible effect on phenolic recovery from chamomile, but also the use of pressures above than 45 bar was proven as needlessly. By using in vitro assays, influence of pressure on antioxidant, cytotoxic and enzyme-inhibitory activities of the extracts was evaluated. Extracts obtained at 30, 45 and 60 bar exhibited stronger bioactivities than at 10 and 90 bar. It was concluded that pressure exert a significant influence on chemical composition of extracts, and thus on biological activity of chamomile extracts.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Subcritical water extraction as a cutting edge technology for the extraction of bioactive compounds from chamomile: Influence of pressure on chemical composition and bioactivity of extracts",
pages = "396-389",
volume = "266",
doi = "10.1016/j.foodchem.2018.06.037",
url = "conv_730"
}

Cvetanović, A., Svarc-Gajić, J., Zeković, Z., Gašić, U., Tešić, Ž., Zengin, G., Masković, P., Mahomoodally, M. F.,& Đurović, S.. (2018). Subcritical water extraction as a cutting edge technology for the extraction of bioactive compounds from chamomile: Influence of pressure on chemical composition and bioactivity of extracts. in Food Chemistry
Elsevier Sci Ltd, Oxford., 266, 389-396.
https://doi.org/10.1016/j.foodchem.2018.06.037
conv_730

Cvetanović A, Svarc-Gajić J, Zeković Z, Gašić U, Tešić Ž, Zengin G, Masković P, Mahomoodally MF, Đurović S. Subcritical water extraction as a cutting edge technology for the extraction of bioactive compounds from chamomile: Influence of pressure on chemical composition and bioactivity of extracts. in Food Chemistry. 2018;266:389-396.
doi:10.1016/j.foodchem.2018.06.037
conv_730 .

Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Zeković, Zoran, Gašić, Uroš, Tešić, Živoslav, Zengin, Gokhan, Masković, Pavle, Mahomoodally, Mohamad Fawzi, Đurović, Saša, "Subcritical water extraction as a cutting edge technology for the extraction of bioactive compounds from chamomile: Influence of pressure on chemical composition and bioactivity of extracts" in Food Chemistry, 266 (2018):389-396,
https://doi.org/10.1016/j.foodchem.2018.06.037 .,
conv_730 .

TY  - JOUR
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Zeković, Zoran
AU  - Masković, Pavle
AU  - Đurović, Saša
AU  - Zengin, Gokhan
AU  - Delerue-Matos, Cristina
AU  - Lozano-Sanchez, Jesus
AU  - Jaksić, Aleksandra
PY  - 2017
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/558
AB  - The present study aimed to evaluate chemical and biological potential of aronia stems for providing new raw material for food and pharmaceutical industries. Aqueous extracts of aronia stems were prepared by three different techniques (microwave-assisted, ultrasound-assisted and subcritical water extraction). For biological activities, antioxidant, antimicrobial and cytotoxic activities were evaluated. For chemical characterisation, phenolic compounds and essential elements were analysed as well as total phenolic contents. Subcritical water extracts exhibited the strongest antioxidant activity with the highest content of phenolics. Minimum inhibitory concentrations for analysed extracts were in the range from 9.76 to 156.25 mu g/mL in antimicrobial assays. The extracts exerted prominent cytotoxicity against different cell lines. Rutin was detected as the major compound in the studied extracts and these extracts were also rich in essential elements. Our study suggested that subcritical water extract of aronia stem could be considered as a new raw material in developing novel functional/industrial products.
T2  - Journal of Supercritical Fluids
T1  - Chemical and biological insights on aronia stems extracts obtained by different extraction techniques: From wastes to functional products
EP  - 181
SP  - 173
VL  - 128
DO  - 10.1016/j.supflu.2017.05.023
UR  - conv_674
ER  - 

@article{
author = "Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Zeković, Zoran and Masković, Pavle and Đurović, Saša and Zengin, Gokhan and Delerue-Matos, Cristina and Lozano-Sanchez, Jesus and Jaksić, Aleksandra",
year = "2017",
abstract = "The present study aimed to evaluate chemical and biological potential of aronia stems for providing new raw material for food and pharmaceutical industries. Aqueous extracts of aronia stems were prepared by three different techniques (microwave-assisted, ultrasound-assisted and subcritical water extraction). For biological activities, antioxidant, antimicrobial and cytotoxic activities were evaluated. For chemical characterisation, phenolic compounds and essential elements were analysed as well as total phenolic contents. Subcritical water extracts exhibited the strongest antioxidant activity with the highest content of phenolics. Minimum inhibitory concentrations for analysed extracts were in the range from 9.76 to 156.25 mu g/mL in antimicrobial assays. The extracts exerted prominent cytotoxicity against different cell lines. Rutin was detected as the major compound in the studied extracts and these extracts were also rich in essential elements. Our study suggested that subcritical water extract of aronia stem could be considered as a new raw material in developing novel functional/industrial products.",
journal = "Journal of Supercritical Fluids",
title = "Chemical and biological insights on aronia stems extracts obtained by different extraction techniques: From wastes to functional products",
pages = "181-173",
volume = "128",
doi = "10.1016/j.supflu.2017.05.023",
url = "conv_674"
}

Cvetanović, A., Svarc-Gajić, J., Zeković, Z., Masković, P., Đurović, S., Zengin, G., Delerue-Matos, C., Lozano-Sanchez, J.,& Jaksić, A.. (2017). Chemical and biological insights on aronia stems extracts obtained by different extraction techniques: From wastes to functional products. in Journal of Supercritical Fluids, 128, 173-181.
https://doi.org/10.1016/j.supflu.2017.05.023
conv_674

Cvetanović A, Svarc-Gajić J, Zeković Z, Masković P, Đurović S, Zengin G, Delerue-Matos C, Lozano-Sanchez J, Jaksić A. Chemical and biological insights on aronia stems extracts obtained by different extraction techniques: From wastes to functional products. in Journal of Supercritical Fluids. 2017;128:173-181.
doi:10.1016/j.supflu.2017.05.023
conv_674 .

Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Zeković, Zoran, Masković, Pavle, Đurović, Saša, Zengin, Gokhan, Delerue-Matos, Cristina, Lozano-Sanchez, Jesus, Jaksić, Aleksandra, "Chemical and biological insights on aronia stems extracts obtained by different extraction techniques: From wastes to functional products" in Journal of Supercritical Fluids, 128 (2017):173-181,
https://doi.org/10.1016/j.supflu.2017.05.023 .,
conv_674 .

TY  - JOUR
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Gašić, Uroš
AU  - Tešić, Živoslav
AU  - Zengin, Gokhan
AU  - Zeković, Zoran
AU  - Đurović, Saša
PY  - 2017
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/553
AB  - Apigenin is a phytochemical which has been associated with numerous beneficial health effects. However, due to its low concentration and poor bioavailability, isolation from natural sources is very difficult. Subcritical water (SCW) is an excellent solvent for the extraction of moderately polar and non-polar flavonoids. Carefully balanced moderate hydrolytical potential of SCW was used in this work to liberate apigenin from its bound forms. In this research simultaneous extraction and hydrolysis of apigenin bound forms from chamomile have been performed. Optimal operation parameters for maximum yields of apigenin have been investigated and defined (solvent-to-sample ratio 1:30; agitation rate 3 Hz; pressure 45 bar; temperature 115 degrees C; time 30 min). Apigenin was further isolated in its pure form from water extracts obtained under optimal conditions using column chromatography. The purity of isolated compound was confirmed by spectroscopic analysis. Biological activity of extracts obtained under optimal conditions were determined as well. In order to identify polyphenolic compounds UHPLC-HESI-MS/MS analysis was performed.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Supercritical Fluids
T1  - Isolation of apigenin from subcritical water extracts: Optimization of the process
EP  - 42
SP  - 32
VL  - 120
DO  - 10.1016/j.supflu.2016.10.012
UR  - conv_640
ER  - 

@article{
author = "Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Gašić, Uroš and Tešić, Živoslav and Zengin, Gokhan and Zeković, Zoran and Đurović, Saša",
year = "2017",
abstract = "Apigenin is a phytochemical which has been associated with numerous beneficial health effects. However, due to its low concentration and poor bioavailability, isolation from natural sources is very difficult. Subcritical water (SCW) is an excellent solvent for the extraction of moderately polar and non-polar flavonoids. Carefully balanced moderate hydrolytical potential of SCW was used in this work to liberate apigenin from its bound forms. In this research simultaneous extraction and hydrolysis of apigenin bound forms from chamomile have been performed. Optimal operation parameters for maximum yields of apigenin have been investigated and defined (solvent-to-sample ratio 1:30; agitation rate 3 Hz; pressure 45 bar; temperature 115 degrees C; time 30 min). Apigenin was further isolated in its pure form from water extracts obtained under optimal conditions using column chromatography. The purity of isolated compound was confirmed by spectroscopic analysis. Biological activity of extracts obtained under optimal conditions were determined as well. In order to identify polyphenolic compounds UHPLC-HESI-MS/MS analysis was performed.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Isolation of apigenin from subcritical water extracts: Optimization of the process",
pages = "42-32",
volume = "120",
doi = "10.1016/j.supflu.2016.10.012",
url = "conv_640"
}

Cvetanović, A., Svarc-Gajić, J., Gašić, U., Tešić, Ž., Zengin, G., Zeković, Z.,& Đurović, S.. (2017). Isolation of apigenin from subcritical water extracts: Optimization of the process. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 120, 32-42.
https://doi.org/10.1016/j.supflu.2016.10.012
conv_640

Cvetanović A, Svarc-Gajić J, Gašić U, Tešić Ž, Zengin G, Zeković Z, Đurović S. Isolation of apigenin from subcritical water extracts: Optimization of the process. in Journal of Supercritical Fluids. 2017;120:32-42.
doi:10.1016/j.supflu.2016.10.012
conv_640 .

Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Gašić, Uroš, Tešić, Živoslav, Zengin, Gokhan, Zeković, Zoran, Đurović, Saša, "Isolation of apigenin from subcritical water extracts: Optimization of the process" in Journal of Supercritical Fluids, 120 (2017):32-42,
https://doi.org/10.1016/j.supflu.2016.10.012 .,
conv_640 .

TY  - JOUR
AU  - Đurović, Saša
AU  - Pavlić, Branimir
AU  - Sorgić, Sasa
AU  - Popov, Sasa
AU  - Savić, Sasa
AU  - Pertonijević, Mirjana
AU  - Radojković, Marija
AU  - Cvetanović, Aleksandra
AU  - Zeković, Zoran
PY  - 2017
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/538
AB  - Urtica dioica L. (stinging nettle) is annual plant which possesses wide range of biological effects and being used in folk medicine since the ancient times. Despite the numerous studies concerning the biological activities of this plant, there are only several studies regarding the chemical composition of stinging nettle (SN) leaves. Deeper chemical investigation revealed the presence of different class of compounds (polyphenols, phenolic acids, fatty acids, carotenoids, elements and minerals) in SN leaves. Results showed the chlorophylls and carotenoids contents of 304.63 mg 100 g(-1) and 69.07 mg 100 g(-1), respectively. The most abundant fatty acids were C18:3 (67.98 mu g g(-1)), C16:0 (60.97 mu g g(-1)) and C18:2 (55.99 mu g g(-1)), among terpenes linalool was dominant compound (5.1 mg g(-1)), while dominant trace element was iron with the content of 150.97 mu g g(-1). Such chemical profile is significant and indicate the wide range of possible further usage of this plant.
PB  - Elsevier
T2  - Journal of Functional Foods
T1  - Chemical composition of stinging nettle leaves obtained by different analytical approaches
EP  - 26
SP  - 18
VL  - 32
DO  - 10.1016/j.jff.2017.02.019
UR  - conv_656
ER  - 

@article{
author = "Đurović, Saša and Pavlić, Branimir and Sorgić, Sasa and Popov, Sasa and Savić, Sasa and Pertonijević, Mirjana and Radojković, Marija and Cvetanović, Aleksandra and Zeković, Zoran",
year = "2017",
abstract = "Urtica dioica L. (stinging nettle) is annual plant which possesses wide range of biological effects and being used in folk medicine since the ancient times. Despite the numerous studies concerning the biological activities of this plant, there are only several studies regarding the chemical composition of stinging nettle (SN) leaves. Deeper chemical investigation revealed the presence of different class of compounds (polyphenols, phenolic acids, fatty acids, carotenoids, elements and minerals) in SN leaves. Results showed the chlorophylls and carotenoids contents of 304.63 mg 100 g(-1) and 69.07 mg 100 g(-1), respectively. The most abundant fatty acids were C18:3 (67.98 mu g g(-1)), C16:0 (60.97 mu g g(-1)) and C18:2 (55.99 mu g g(-1)), among terpenes linalool was dominant compound (5.1 mg g(-1)), while dominant trace element was iron with the content of 150.97 mu g g(-1). Such chemical profile is significant and indicate the wide range of possible further usage of this plant.",
publisher = "Elsevier",
journal = "Journal of Functional Foods",
title = "Chemical composition of stinging nettle leaves obtained by different analytical approaches",
pages = "26-18",
volume = "32",
doi = "10.1016/j.jff.2017.02.019",
url = "conv_656"
}

Đurović, S., Pavlić, B., Sorgić, S., Popov, S., Savić, S., Pertonijević, M., Radojković, M., Cvetanović, A.,& Zeković, Z.. (2017). Chemical composition of stinging nettle leaves obtained by different analytical approaches. in Journal of Functional Foods
Elsevier., 32, 18-26.
https://doi.org/10.1016/j.jff.2017.02.019
conv_656

Đurović S, Pavlić B, Sorgić S, Popov S, Savić S, Pertonijević M, Radojković M, Cvetanović A, Zeković Z. Chemical composition of stinging nettle leaves obtained by different analytical approaches. in Journal of Functional Foods. 2017;32:18-26.
doi:10.1016/j.jff.2017.02.019
conv_656 .

Đurović, Saša, Pavlić, Branimir, Sorgić, Sasa, Popov, Sasa, Savić, Sasa, Pertonijević, Mirjana, Radojković, Marija, Cvetanović, Aleksandra, Zeković, Zoran, "Chemical composition of stinging nettle leaves obtained by different analytical approaches" in Journal of Functional Foods, 32 (2017):18-26,
https://doi.org/10.1016/j.jff.2017.02.019 .,
conv_656 .

TY  - JOUR
AU  - Zeković, Zoran
AU  - Bera, Oskar
AU  - Đurović, Saša
AU  - Pavlić, Branimir
PY  - 2017
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/527
AB  - The main goal of this research was mathematical modelling and numerical simulation of the supercritical fluid extraction (SFE) process of coriander (Coriandrum sativum L.) seeds. SFE was performed at different set of process parameters: pressure (100, 150 and 200 bar), temperature (40, 55 and 70 degrees C) and CO2 flow rate (0.2, 0.3 and 0.4kg/h). Both applied empirical models, derived from models developed by Brunner and Esquivel et al., adequately described SFE process. Second objective was to determine effects of investigated SFE parameters on total extraction yield. Furthermore, calculated parameters from the empirical models were used for the calculation of initial slope, which was successfully used for optimization using artificial neural network (ANN). Optimized SFE conditions for maximized initial slope, i.e. initial rate of the solubility-controlled extraction phase, were pressure of 200 bar, temperature of 40 degrees C and CO2 flow rate of 0.4 kg/h.
T2  - Journal of Supercritical Fluids
T1  - Supercritical fluid extraction of coriander seeds: Kinetics modelling and ANN optimization
EP  - 95
SP  - 88
VL  - 125
DO  - 10.1016/j.supflu.2017.02.006
UR  - conv_652
ER  - 

@article{
author = "Zeković, Zoran and Bera, Oskar and Đurović, Saša and Pavlić, Branimir",
year = "2017",
abstract = "The main goal of this research was mathematical modelling and numerical simulation of the supercritical fluid extraction (SFE) process of coriander (Coriandrum sativum L.) seeds. SFE was performed at different set of process parameters: pressure (100, 150 and 200 bar), temperature (40, 55 and 70 degrees C) and CO2 flow rate (0.2, 0.3 and 0.4kg/h). Both applied empirical models, derived from models developed by Brunner and Esquivel et al., adequately described SFE process. Second objective was to determine effects of investigated SFE parameters on total extraction yield. Furthermore, calculated parameters from the empirical models were used for the calculation of initial slope, which was successfully used for optimization using artificial neural network (ANN). Optimized SFE conditions for maximized initial slope, i.e. initial rate of the solubility-controlled extraction phase, were pressure of 200 bar, temperature of 40 degrees C and CO2 flow rate of 0.4 kg/h.",
journal = "Journal of Supercritical Fluids",
title = "Supercritical fluid extraction of coriander seeds: Kinetics modelling and ANN optimization",
pages = "95-88",
volume = "125",
doi = "10.1016/j.supflu.2017.02.006",
url = "conv_652"
}

Zeković, Z., Bera, O., Đurović, S.,& Pavlić, B.. (2017). Supercritical fluid extraction of coriander seeds: Kinetics modelling and ANN optimization. in Journal of Supercritical Fluids, 125, 88-95.
https://doi.org/10.1016/j.supflu.2017.02.006
conv_652

Zeković Z, Bera O, Đurović S, Pavlić B. Supercritical fluid extraction of coriander seeds: Kinetics modelling and ANN optimization. in Journal of Supercritical Fluids. 2017;125:88-95.
doi:10.1016/j.supflu.2017.02.006
conv_652 .

Zeković, Zoran, Bera, Oskar, Đurović, Saša, Pavlić, Branimir, "Supercritical fluid extraction of coriander seeds: Kinetics modelling and ANN optimization" in Journal of Supercritical Fluids, 125 (2017):88-95,
https://doi.org/10.1016/j.supflu.2017.02.006 .,
conv_652 .

TY  - JOUR
AU  - Zeković, Zoran
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Gorjanović, Stanislava
AU  - Sužnjević, Desanka
AU  - Masković, Pavle
AU  - Savić, Sasa
AU  - Radojković, Marija
AU  - Đurović, Saša
PY  - 2017
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/510
AB  - Biologically active compounds were isolated from stinging nettle (Urtica dioica L.) leaves using non-conventional extraction techniques such as ultrasound-assisted (UAE), microwave-assisted (MAE) and subcritical water extraction (SCW). Based on the extraction efficiency of six various solvents determined preliminary, water was selected as appropriate solvent for further extraction. The highest total phenolics (463.59 mg CAE/g SN) and flavonoids (11.00 mg CE/g SN) contents, and antioxidant activity (DPPH radical scavenging (IC50 = 16.93 mu g/mL), reducing power (EC50 = 30.07 mu g/mL) and polarographic assays (HPMC = 243.2%/mL) were ascribed to SCW extract. Cytotoxic and antimicrobial assays also confirmed domination of SCW technique. Superior cytotoxic activity against Hep2c, RD and L2OB cell lines (13.42 mu g/mL, 9.69 mu g/mL and 7.52 mu g/mL, respectively) and potent antimicrobial activity extract against Staphylococcus aureus (MIC = 9.76 mu g/mL) were also observed. The highest number of individual phenolic compounds were found in MAE extract. Rutin was identified as the most dominant compound in UAE, MAE and SCW extracts (578.36 mu g/g, 722.83 mu g/g and 215.49 mu g/g, respectively), while sinapic acid as the most dominant phenolic acid (50.49 mu g/g, 63.12 mu g/g and 18.08 mu g/g, respectively).
T2  - Industrial Crops and Products
T1  - Chemical and biological screening of stinging nettle leaves extracts obtained by modern extraction techniques
EP  - 430
SP  - 423
VL  - 108
DO  - 10.1016/j.indcrop.2017.06.055
UR  - conv_686
ER  - 

@article{
author = "Zeković, Zoran and Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Gorjanović, Stanislava and Sužnjević, Desanka and Masković, Pavle and Savić, Sasa and Radojković, Marija and Đurović, Saša",
year = "2017",
abstract = "Biologically active compounds were isolated from stinging nettle (Urtica dioica L.) leaves using non-conventional extraction techniques such as ultrasound-assisted (UAE), microwave-assisted (MAE) and subcritical water extraction (SCW). Based on the extraction efficiency of six various solvents determined preliminary, water was selected as appropriate solvent for further extraction. The highest total phenolics (463.59 mg CAE/g SN) and flavonoids (11.00 mg CE/g SN) contents, and antioxidant activity (DPPH radical scavenging (IC50 = 16.93 mu g/mL), reducing power (EC50 = 30.07 mu g/mL) and polarographic assays (HPMC = 243.2%/mL) were ascribed to SCW extract. Cytotoxic and antimicrobial assays also confirmed domination of SCW technique. Superior cytotoxic activity against Hep2c, RD and L2OB cell lines (13.42 mu g/mL, 9.69 mu g/mL and 7.52 mu g/mL, respectively) and potent antimicrobial activity extract against Staphylococcus aureus (MIC = 9.76 mu g/mL) were also observed. The highest number of individual phenolic compounds were found in MAE extract. Rutin was identified as the most dominant compound in UAE, MAE and SCW extracts (578.36 mu g/g, 722.83 mu g/g and 215.49 mu g/g, respectively), while sinapic acid as the most dominant phenolic acid (50.49 mu g/g, 63.12 mu g/g and 18.08 mu g/g, respectively).",
journal = "Industrial Crops and Products",
title = "Chemical and biological screening of stinging nettle leaves extracts obtained by modern extraction techniques",
pages = "430-423",
volume = "108",
doi = "10.1016/j.indcrop.2017.06.055",
url = "conv_686"
}

Zeković, Z., Cvetanović, A., Svarc-Gajić, J., Gorjanović, S., Sužnjević, D., Masković, P., Savić, S., Radojković, M.,& Đurović, S.. (2017). Chemical and biological screening of stinging nettle leaves extracts obtained by modern extraction techniques. in Industrial Crops and Products, 108, 423-430.
https://doi.org/10.1016/j.indcrop.2017.06.055
conv_686

Zeković Z, Cvetanović A, Svarc-Gajić J, Gorjanović S, Sužnjević D, Masković P, Savić S, Radojković M, Đurović S. Chemical and biological screening of stinging nettle leaves extracts obtained by modern extraction techniques. in Industrial Crops and Products. 2017;108:423-430.
doi:10.1016/j.indcrop.2017.06.055
conv_686 .

Zeković, Zoran, Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Gorjanović, Stanislava, Sužnjević, Desanka, Masković, Pavle, Savić, Sasa, Radojković, Marija, Đurović, Saša, "Chemical and biological screening of stinging nettle leaves extracts obtained by modern extraction techniques" in Industrial Crops and Products, 108 (2017):423-430,
https://doi.org/10.1016/j.indcrop.2017.06.055 .,
conv_686 .

TY  - JOUR
AU  - Masković, Pavle
AU  - Veličković, Vesna
AU  - Mitić, Milan
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Radojković, Marija
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Vujić, Jelena
PY  - 2017
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/506
AB  - Satureja hortensis L. (summer savory) is herb from Lamiaceae plant family known by its usage in folk medicine and cooking. Despite these facts, this plant was not well studied regarding the application of nonconventional extraction techniques and utilization of prepared extracts. Thus, aim of this study was to prepare extract using conventional (maceration and Soxhlet) and non-conventional (ultrasound-assisted, microwave-assisted and subcritical water) approaches, to establish their chemical profile and biological activity using different assays and methods. Results confirmed the domination of subcritical water approach for isolation of natural compounds, following by microwave-assisted extraction. High performance liquid chromatography with photodiode array detection (HPLC-PDA) analysis confirmed the presence and domination of rosmarinic acid in conventionally prepared extracts, while rutin and quercetin dominated in non-conventionally prepared ones. Antioxidant and cytotoxic assays followed the trends of previous analysis, where the highest activity was exhibited by subcritical extract. Thus, results showed that extracts may be applied in food and pharmaceutical industries for utilization.
T2  - Industrial Crops and Products
T1  - Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity
EP  - 881
SP  - 875
VL  - 109
DO  - 10.1016/j.indcrop.2017.09.063
UR  - conv_691
ER  - 

@article{
author = "Masković, Pavle and Veličković, Vesna and Mitić, Milan and Đurović, Saša and Zeković, Zoran and Radojković, Marija and Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Vujić, Jelena",
year = "2017",
abstract = "Satureja hortensis L. (summer savory) is herb from Lamiaceae plant family known by its usage in folk medicine and cooking. Despite these facts, this plant was not well studied regarding the application of nonconventional extraction techniques and utilization of prepared extracts. Thus, aim of this study was to prepare extract using conventional (maceration and Soxhlet) and non-conventional (ultrasound-assisted, microwave-assisted and subcritical water) approaches, to establish their chemical profile and biological activity using different assays and methods. Results confirmed the domination of subcritical water approach for isolation of natural compounds, following by microwave-assisted extraction. High performance liquid chromatography with photodiode array detection (HPLC-PDA) analysis confirmed the presence and domination of rosmarinic acid in conventionally prepared extracts, while rutin and quercetin dominated in non-conventionally prepared ones. Antioxidant and cytotoxic assays followed the trends of previous analysis, where the highest activity was exhibited by subcritical extract. Thus, results showed that extracts may be applied in food and pharmaceutical industries for utilization.",
journal = "Industrial Crops and Products",
title = "Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity",
pages = "881-875",
volume = "109",
doi = "10.1016/j.indcrop.2017.09.063",
url = "conv_691"
}

Masković, P., Veličković, V., Mitić, M., Đurović, S., Zeković, Z., Radojković, M., Cvetanović, A., Svarc-Gajić, J.,& Vujić, J.. (2017). Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity. in Industrial Crops and Products, 109, 875-881.
https://doi.org/10.1016/j.indcrop.2017.09.063
conv_691

Masković P, Veličković V, Mitić M, Đurović S, Zeković Z, Radojković M, Cvetanović A, Svarc-Gajić J, Vujić J. Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity. in Industrial Crops and Products. 2017;109:875-881.
doi:10.1016/j.indcrop.2017.09.063
conv_691 .

Masković, Pavle, Veličković, Vesna, Mitić, Milan, Đurović, Saša, Zeković, Zoran, Radojković, Marija, Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Vujić, Jelena, "Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity" in Industrial Crops and Products, 109 (2017):875-881,
https://doi.org/10.1016/j.indcrop.2017.09.063 .,
conv_691 .