TY  - JOUR
AU  - Masković, Pavle
AU  - Veličković, Vesna
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Radojković, Marija
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Mitić, Milan
AU  - Vujić, Jelena
PY  - 2018
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/604
AB  - Background: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. Purpose: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. Study design and methods: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. Results and conclusion: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.
T2  - Phytomedicine
T1  - Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches
EP  - 124
SP  - 118
VL  - 38
DO  - 10.1016/j.phymed.2017.11.010
UR  - conv_708
ER  - 

@article{
author = "Masković, Pavle and Veličković, Vesna and Đurović, Saša and Zeković, Zoran and Radojković, Marija and Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Mitić, Milan and Vujić, Jelena",
year = "2018",
abstract = "Background: Lavatera thuringiaca L. is herbaceous perennial plant from Malvaceae family, which is known for its biological activity and richness in polyphenolic compounds. Despite this, the information regarding the biological activity and chemical profile is still insufficient. Purpose: Aim of this study was to investigate biological potential and chemical profile of Lavatera thuringiaca L., as well as influence of applied extraction technique on them. Study design and methods: Two conventional and four non-conventional extraction techniques were applied in order to obtain extracts rich in bioactive compound. Extracts were further tested for total phenolics, flavonoids, condensed tannins, gallotannins and anthocyanins contents using spectrophotometric assays. Polyphenolic profile was established using HPLC-DAD analysis. Biological activity was investigated regarding antioxidant, cytotoxic and antibacterial activities. Four antioxidant assays were applied as well as three different cell lines for cytotoxic and fifteen bacterial strain for antibacterial activity. Results and conclusion: Results showed that subcritical water extraction (SCW) dominated over the other extraction techniques, where SCW extract exhibited the highest biological activity. Study indicates that plant Lavatera thuringiaca L. may be used as a potential source of biologically compounds.",
journal = "Phytomedicine",
title = "Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches",
pages = "124-118",
volume = "38",
doi = "10.1016/j.phymed.2017.11.010",
url = "conv_708"
}

Masković, P., Veličković, V., Đurović, S., Zeković, Z., Radojković, M., Cvetanović, A., Svarc-Gajić, J., Mitić, M.,& Vujić, J.. (2018). Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches. in Phytomedicine, 38, 118-124.
https://doi.org/10.1016/j.phymed.2017.11.010
conv_708

Masković P, Veličković V, Đurović S, Zeković Z, Radojković M, Cvetanović A, Svarc-Gajić J, Mitić M, Vujić J. Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches. in Phytomedicine. 2018;38:118-124.
doi:10.1016/j.phymed.2017.11.010
conv_708 .

Masković, Pavle, Veličković, Vesna, Đurović, Saša, Zeković, Zoran, Radojković, Marija, Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Mitić, Milan, Vujić, Jelena, "Biological activity and chemical profile of Lavatera thuringiaca L. extracts obtained by different extraction approaches" in Phytomedicine, 38 (2018):118-124,
https://doi.org/10.1016/j.phymed.2017.11.010 .,
conv_708 .

TY  - JOUR
AU  - Masković, Pavle
AU  - Radojković, Marija
AU  - Cvetanović, Aleksandra
AU  - Mitić, Milan
AU  - Zeković, Zoran
AU  - Đurović, Saša
PY  - 2018
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/585
AB  - Fruits of Prunus cerasus L. (tart cherry) represent a significant source of health beneficial compounds and have been widely used in food industry. Despite that, other plant parts, such as twigs, have not been investigated. Aim of this study was to investigate chemical profile of twig extracts prepared from plant material of three cultivars. Wig extracts were prepared using maceration and Soxhlet extraction approaches, and investigated regarding phenolics (5.85-14.80 mg.l(-1)) and saccharides (123.38-339.46 g.l(-1)) concentrations using high performance liquid chromatography (HPLC) analysis. Total phenolics (99.34-139.77 g.kg(-1)), flavonoids (14.18-42.88 g.kg(-1)), anthocyanins (76.71-84.97 g.kg(-1)), condensed tannins (52.65-79.76 g.kg(-1)) and gallotannins (19.03-37.23 g.kg(-1)) contents were determined using spectrophotometric analysis. Biological activity was investigated using four antioxidant assays (total antioxidant capacity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, lipid peroxidation assay and hydroxyl radical-scavenging activity). Cytotoxic activity was assessed on three different cell lines (Hep2c, RD and L2OB), while antimicrobial activity was established on 15 bacterial strains. Obtained results confirmed the presence of health beneficial compounds in twigs and indicated the possibility of utilization as a secondary source of those compounds.
PB  - Food Reseach Institute
T2  - Journal of Food and Nutrition Research
T1  - Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization
EP  - 230
IS  - 3
SP  - 222
VL  - 57
UR  - conv_1196
ER  - 

@article{
author = "Masković, Pavle and Radojković, Marija and Cvetanović, Aleksandra and Mitić, Milan and Zeković, Zoran and Đurović, Saša",
year = "2018",
abstract = "Fruits of Prunus cerasus L. (tart cherry) represent a significant source of health beneficial compounds and have been widely used in food industry. Despite that, other plant parts, such as twigs, have not been investigated. Aim of this study was to investigate chemical profile of twig extracts prepared from plant material of three cultivars. Wig extracts were prepared using maceration and Soxhlet extraction approaches, and investigated regarding phenolics (5.85-14.80 mg.l(-1)) and saccharides (123.38-339.46 g.l(-1)) concentrations using high performance liquid chromatography (HPLC) analysis. Total phenolics (99.34-139.77 g.kg(-1)), flavonoids (14.18-42.88 g.kg(-1)), anthocyanins (76.71-84.97 g.kg(-1)), condensed tannins (52.65-79.76 g.kg(-1)) and gallotannins (19.03-37.23 g.kg(-1)) contents were determined using spectrophotometric analysis. Biological activity was investigated using four antioxidant assays (total antioxidant capacity, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, lipid peroxidation assay and hydroxyl radical-scavenging activity). Cytotoxic activity was assessed on three different cell lines (Hep2c, RD and L2OB), while antimicrobial activity was established on 15 bacterial strains. Obtained results confirmed the presence of health beneficial compounds in twigs and indicated the possibility of utilization as a secondary source of those compounds.",
publisher = "Food Reseach Institute",
journal = "Journal of Food and Nutrition Research",
title = "Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization",
pages = "230-222",
number = "3",
volume = "57",
url = "conv_1196"
}

Masković, P., Radojković, M., Cvetanović, A., Mitić, M., Zeković, Z.,& Đurović, S.. (2018). Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization. in Journal of Food and Nutrition Research
Food Reseach Institute., 57(3), 222-230.
conv_1196

Masković P, Radojković M, Cvetanović A, Mitić M, Zeković Z, Đurović S. Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization. in Journal of Food and Nutrition Research. 2018;57(3):222-230.
conv_1196 .

Masković, Pavle, Radojković, Marija, Cvetanović, Aleksandra, Mitić, Milan, Zeković, Zoran, Đurović, Saša, "Chemical profile and biological activity of tart cherry twigs: possibilities of plant waste utilization" in Journal of Food and Nutrition Research, 57, no. 3 (2018):222-230,
conv_1196 .

TY  - JOUR
AU  - Masković, Pavle
AU  - Veličković, Vesna
AU  - Mitić, Milan
AU  - Đurović, Saša
AU  - Zeković, Zoran
AU  - Radojković, Marija
AU  - Cvetanović, Aleksandra
AU  - Svarc-Gajić, Jaroslava
AU  - Vujić, Jelena
PY  - 2017
UR  - https://riofh.iofh.bg.ac.rs/handle/123456789/506
AB  - Satureja hortensis L. (summer savory) is herb from Lamiaceae plant family known by its usage in folk medicine and cooking. Despite these facts, this plant was not well studied regarding the application of nonconventional extraction techniques and utilization of prepared extracts. Thus, aim of this study was to prepare extract using conventional (maceration and Soxhlet) and non-conventional (ultrasound-assisted, microwave-assisted and subcritical water) approaches, to establish their chemical profile and biological activity using different assays and methods. Results confirmed the domination of subcritical water approach for isolation of natural compounds, following by microwave-assisted extraction. High performance liquid chromatography with photodiode array detection (HPLC-PDA) analysis confirmed the presence and domination of rosmarinic acid in conventionally prepared extracts, while rutin and quercetin dominated in non-conventionally prepared ones. Antioxidant and cytotoxic assays followed the trends of previous analysis, where the highest activity was exhibited by subcritical extract. Thus, results showed that extracts may be applied in food and pharmaceutical industries for utilization.
T2  - Industrial Crops and Products
T1  - Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity
EP  - 881
SP  - 875
VL  - 109
DO  - 10.1016/j.indcrop.2017.09.063
UR  - conv_691
ER  - 

@article{
author = "Masković, Pavle and Veličković, Vesna and Mitić, Milan and Đurović, Saša and Zeković, Zoran and Radojković, Marija and Cvetanović, Aleksandra and Svarc-Gajić, Jaroslava and Vujić, Jelena",
year = "2017",
abstract = "Satureja hortensis L. (summer savory) is herb from Lamiaceae plant family known by its usage in folk medicine and cooking. Despite these facts, this plant was not well studied regarding the application of nonconventional extraction techniques and utilization of prepared extracts. Thus, aim of this study was to prepare extract using conventional (maceration and Soxhlet) and non-conventional (ultrasound-assisted, microwave-assisted and subcritical water) approaches, to establish their chemical profile and biological activity using different assays and methods. Results confirmed the domination of subcritical water approach for isolation of natural compounds, following by microwave-assisted extraction. High performance liquid chromatography with photodiode array detection (HPLC-PDA) analysis confirmed the presence and domination of rosmarinic acid in conventionally prepared extracts, while rutin and quercetin dominated in non-conventionally prepared ones. Antioxidant and cytotoxic assays followed the trends of previous analysis, where the highest activity was exhibited by subcritical extract. Thus, results showed that extracts may be applied in food and pharmaceutical industries for utilization.",
journal = "Industrial Crops and Products",
title = "Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity",
pages = "881-875",
volume = "109",
doi = "10.1016/j.indcrop.2017.09.063",
url = "conv_691"
}

Masković, P., Veličković, V., Mitić, M., Đurović, S., Zeković, Z., Radojković, M., Cvetanović, A., Svarc-Gajić, J.,& Vujić, J.. (2017). Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity. in Industrial Crops and Products, 109, 875-881.
https://doi.org/10.1016/j.indcrop.2017.09.063
conv_691

Masković P, Veličković V, Mitić M, Đurović S, Zeković Z, Radojković M, Cvetanović A, Svarc-Gajić J, Vujić J. Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity. in Industrial Crops and Products. 2017;109:875-881.
doi:10.1016/j.indcrop.2017.09.063
conv_691 .

Masković, Pavle, Veličković, Vesna, Mitić, Milan, Đurović, Saša, Zeković, Zoran, Radojković, Marija, Cvetanović, Aleksandra, Svarc-Gajić, Jaroslava, Vujić, Jelena, "Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity" in Industrial Crops and Products, 109 (2017):875-881,
https://doi.org/10.1016/j.indcrop.2017.09.063 .,
conv_691 .